Advertisement

The Physical Basis of Biochemistry

The Foundations of Molecular Biophysics

  • Peter R. Bergethon

Table of contents

  1. Front Matter
    Pages i-xxii
  2. The Science and Philosophy of Biophysical Study

  3. Physical Foundations

    1. Front Matter
      Pages 41-41
    2. Peter R. Bergethon
      Pages 48-67
    3. Peter R. Bergethon
      Pages 68-96
    4. Peter R. Bergethon
      Pages 97-108
    5. Peter R. Bergethon
      Pages 109-124
    6. Peter R. Bergethon
      Pages 125-157
    7. Peter R. Bergethon
      Pages 158-172
  4. Measuring a System: Tools for Exploring Natural State Space

    1. Front Matter
      Pages 173-173
    2. Peter R. Bergethon
      Pages 249-267
    3. Peter R. Bergethon
      Pages 268-281
    4. Peter R. Bergethon
      Pages 282-283
  5. The Structure of Biological State Space: Building a Model of Aqueous Biochemistry

    1. Front Matter
      Pages 285-285
    2. Peter R. Bergethon
      Pages 287-299
    3. Peter R. Bergethon
      Pages 300-318
    4. Peter R. Bergethon
      Pages 319-329
    5. Peter R. Bergethon
      Pages 346-360
    6. Peter R. Bergethon
      Pages 361-393
    7. Peter R. Bergethon
      Pages 394-414
    8. Peter R. Bergethon
      Pages 415-426
    9. Peter R. Bergethon
      Pages 427-438
  6. Function and Action in State Space

    1. Front Matter
      Pages 439-439
    2. Peter R. Bergethon
      Pages 441-444
    3. Peter R. Bergethon
      Pages 445-454
    4. Peter R. Bergethon
      Pages 455-469
    5. Peter R. Bergethon
      Pages 470-479
    6. Peter R. Bergethon
      Pages 480-497
    7. Peter R. Bergethon
      Pages 498-515
  7. Epilogue

    1. Peter R. Bergethon
      Pages 516-516
  8. Back Matter
    Pages 517-567

About this book

Introduction

The objective of this book is to provide a unifying approach to the study of biophysical chemistry for the advanced undergraduate who has had a year of physics, organic chem­ istry, calculus, and biology. This book began as a revised edition of Biophysical Chemistry: Molecules to Membranes, which Elizabeth Simons and I coauthored. That short volume was written in an attempt to provide a concise text for a one-semester course in biophysical chemistry at the graduate level. The experience of teaching biophysical chemistry to bi­ ologically oriented students over the last decade has made it clear that the subject requires a more fundamental text that unifies the many threads of modem science: physics, chem­ istry, biology, mathematics, and statistics. This book represents that effort. This volume is not a treatment of modem biophysical chemistry with its rich history and many contro­ versies, although a book on that topic is also needed. The Physical Basis of Biochemistry is an introduction to the philosophy and practice of an interdisciplinary field in which biological systems are explored using the quantitative perspective of the physical scientist. I have three primary objectives in this volume: one, to provide a unifying picture of the interdisciplinary threads from which the tapestry of biophysical studies is woven; two, to provide an insight into the power of the modeling approach to scientific investigation; and three, to communicate a sense of excitement for the activity and wholesome argument that characterize this field of study.

Keywords

Bergethon biochemistry biology biophysics chemistry membrane molecular biophysics physical biochemistry physical chemistry

Authors and affiliations

  • Peter R. Bergethon
    • 1
  1. 1.Department of BiochemistryBoston University School of MedicineBostonUSA

Bibliographic information