Pathological Neurochemistry

  • Abel Lajtha

Table of contents

  1. Front Matter
    Pages i-xxx
  2. Salvatore DiMauro, Darryl C. De Vivo
    Pages 1-13
  3. F. A. Hommes
    Pages 15-41
  4. John E. Morley, Charles J. Billington
    Pages 43-65
  5. Samuel Bogoch, S. Winston Bogoch
    Pages 67-80
  6. Roscoe O. Brady
    Pages 81-97
  7. Hugo W. Moser
    Pages 99-118
  8. Yasuo Kishimoto, Hugo W. Moser, Kunihiko Suzuki
    Pages 125-151
  9. Pak Hoo Chan, Robert A. Fishman
    Pages 153-174
  10. Jørgen Clausen
    Pages 175-205
  11. George A. Hashim
    Pages 207-223
  12. Ara Tourian
    Pages 225-240
  13. Edward L. Hogan, Naren L. Banik
    Pages 285-337
  14. Claude G. Wasterlain, Anne M. Morin, Barney E. Dwyer
    Pages 339-419
  15. Theodore A. Hare, James H. Wood
    Pages 421-447
  16. A. Lowenthal, D. Karcher
    Pages 449-459
  17. Susan Y. Schmidt
    Pages 461-507
  18. Erik Lycke
    Pages 509-532
  19. Stanley B. Prusiner, Ashley T. Haase
    Pages 533-552
  20. Lynn Eleanor DeLisi, Richard Jed Wyatt
    Pages 553-587
  21. Karl Verebey, Mark S. Gold
    Pages 589-615
  22. Steven T. DeKosky, Norman H. Bass
    Pages 617-650
  23. F. Petty, A. D. Sherman, G. Winokur
    Pages 651-669
  24. A. Yuwiler, E. Geller, E. Ritvo
    Pages 671-691
  25. L. Battistin, M. Dam
    Pages 693-730
  26. M. B. H. Youdim
    Pages 731-755
  27. Pierre M. Dreyfus
    Pages 757-777
  28. Allan Elliott
    Pages 779-781
  29. Back Matter
    Pages 783-792

About this book


More than for any other volume of the Handbook of Neurochemistry, the chap­ ters in this volume on Pathological Neurochemistry deal with the interface of the laboratory bench with the patient's bedside. Most of the chapters reflect the confluence of basic scientists, clinical investigators, and physicians. Con­ sidered here are many of the more important disorders that afflict the nerves, muscles, spinal cord, and/or brain of mankind throughout the world. There are well over 500 such disorders. And our understanding of their nature and of measures for effective prevention or treatment depends significantly on appli­ cation of the biochemical disciplines that characterize neurochemistry. Before World War II, any attempt to compile a volume on pathological neurochemistry would have been largely descriptive and very rudimentary, as such "handbooks" by Hans Winterstein (1929), Irvine Page (1937), and others demonstrate. But thanks to the many major advances in research and tech­ nology in the postwar decades, we now stand at the threshold of understanding how to manage many of the major neurological disorders, and we may expect more such delineations in the immediate decades ahead. Neurochemistry, de­ fined broadly, has played a central role in this extraordinary turn of events, progressing from what J. L. W, Thudichum in 1884 called objects of anxious empiricism to his anticipation of the proud exercise of chemical precision.


brain muscle neurochemistry spinal cord

Editors and affiliations

  • Abel Lajtha
    • 1
  1. 1.Center for NeurochemistryWards IslandUSA

Bibliographic information