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The Basal Forebrain

Anatomy to Function

  • T. Celeste Napier
  • Peter W. Kalivas
  • Israel Hanin

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 295)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Anatomy of the Basal Forebrain and Related Structures

  3. Electrophysiology and Pharmacology of Basal Forebrain Neurons

    1. William H. Griffith, Joan A. Sim, Robert T. Matthews
      Pages 143-155
    2. Yasuko Nakajima, Peter R. Stanfield, Kazuhiko Yamaguchi, Shigehiro Nakajima
      Pages 157-167
    3. Conrad Chi-Yiu Yim, Lisa Sheehy, Gordon Mogenson
      Pages 169-182
    4. T. Celeste Napier, Mary Beth Muench, Renata J. Maslowski, George Battaglia
      Pages 183-195
    5. James Pirch, Greg Rigdon, Hubert Rucker, Kathy Turco
      Pages 219-231
    6. Russell T. Richardson, Mahlon R. DeLong
      Pages 233-252
  4. Functional and Pharmacologic Evaluations of Basal Forebrain Involvement with Locomotion, Reward and Cognition

    1. George F. Koob, Neal R. Swerdlow, Franco Vaccarino, Carol Hubner, Luigi Pulvirenti, Friedbert Weiss
      Pages 291-305
    2. Steven I. Dworkin, Linda J. Porrino, James E. Smith
      Pages 327-338
    3. Linda J. Porrino, Steven I. Dworkin, James E. Smith
      Pages 339-351
    4. David Olton, Alicja Markowska, Mary Lou Voytko, Ben Givens, Linda Gorman, Gary Wenk
      Pages 353-372
    5. James J. Chrobak, T. Celeste Napier, Israel Hanin, Thomas J. Walsh
      Pages 383-398
    6. Hans C. Fibiger, Geert Damsma, Jamie C. Day
      Pages 399-414
  5. Clinical Manifestation of Basal Forebrain Dysfunction, and Models of this Dysfunction

    1. B. H. Wainer, H. J. Lee, J. D. Roback, D. N. Hammond
      Pages 415-437
    2. Karen Marder, Richard Mayeux
      Pages 439-445
  6. History of Acetylcholine

    1. Alexander G. Karczmar
      Pages 453-477
  7. Back Matter
    Pages 479-489

About this book

Introduction

The basal forebrain has received considerable attention in recent years. This emphasis resulted from observations that the cortically projecting cholinergic neurons found in this region are critical for normal information processing. However, to achieve a complete understanding of such a complex function as "information processing" it is necessary to consider the basal forebrain not as an autonomous structure with a solitary task, but one that plays an integrative role; a structure that is connected intimately with many brain regions. This view evolved from the realization that the basal forebrain interfaces cognitive and reward functions with motor outputs. It is from this integrative and functional perspective that the present book was organized. The book is a unique collection of reports pertaining to the basal forebrain that encompasses a diversity of research approaches and techniques. It provides the reader with a progression of information that begins with anatomical descriptions of the afferent and efferent systems, stressing the integrative nature of various neurotransmitters located within the basal forebrain. The chapters focusing on anatomy are complemented by electrophysiologic studies that merge anatomical concepts with synaptic pharmacology and behavior. In vitro experiments demonstrate physiologic variations in anatomically identified neuronal subtypes and, together with in vivo techniques, provide pharmacologic descriptions of neuronal consequences to various neurotransmitter influences. Additional in vivo reports correlate changes in neuronal activity with specific motivational states and motor behaviors. These functional approaches culminate with behavioral studies that overview current understanding of basal forebrain involvement in mnemonic, reward, and motor processes.

Keywords

anatomy attention forebrain information processing neurons

Editors and affiliations

  • T. Celeste Napier
    • 1
  • Peter W. Kalivas
    • 2
  • Israel Hanin
    • 3
  1. 1.Loyola University of ChicagoStritch School of MedicineMaywoodUSA
  2. 2.College of Veterinary MedicineWashington State UniversityPullmanUSA
  3. 3.Loyola University of ChicagoStritch School of MedicineMaywoodUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4757-0145-6
  • Copyright Information Springer-Verlag US 1991
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-0147-0
  • Online ISBN 978-1-4757-0145-6
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site