• Yoshikuni Mizuno
  • Donald B. Calne
  • R. Horowski

Part of the Advances in Research on Neurodegeneration book series (ARN, volume 2)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Genetic, Growth, and Environmental Factors

  3. Metals and, Free Radicals

    1. Front Matter
      Pages 51-51
    2. C. W. Olanow, D. B. Calne, N. S. Chu, D. P. Perl
      Pages 53-62
    3. Moussa B. H. Youdim, Dorit Ben-Shachar, Peter Riederer
      Pages 63-78
    4. Sten Orrenius, Pierluigi Nicotera
      Pages 93-103
    5. Peter Riederer, Moussa B. H. Youdim
      Pages 105-108
  4. Energy Metabolism and Neurotoxins

    1. Front Matter
      Pages 109-109
    2. Robert Siman, Mary J. Savage, Jill M. Roberts-Lewis
      Pages 141-148
    3. Toshiharu Nagatsu, Makoto Naoi, Toshimitsu Niwa, Mitsuo Yoshida
      Pages 149-159
    4. Yoshikuni Mizuno
      Pages 161-165
  5. Special Topics in Neurodegeneration

  6. Erratum

    1. Yoshikuni Mizuno, Donald B. Calne, R. Horowski
      Pages 223-223

About this book


In 1991, a small annual meeting named "International Winter Conference on Neurodegeneration (lWCN)" was established; the aim of this meeting is to review the neurodegenerative disorders and to attempt to explore how progress might be made in this field, as the neurodegenerative disorders have been emerging to be one of the major causes of morbidity and mortality in modern societies. The first meeting took place in Seefeld, Austria, in February 1992; the topics for the first IWCN were chosen to provide a broad foundation of clinical science, which included the problem of aging, classification of neurodegenerative disorders and of Alzheimer's dis­ natural history, pathology, and clinical neurology ease, Parkinson's disease, and amyotrophic lateral sclerosis. The fundamental pathology underlying these neurodegenerative disorders is neuronal cell death. For the understanding of pathophysiol­ ogy and the development of neuroprotective treatment for these dis­ orders, elucidation of the mechanism of neuronal cell death at the cellular and molecular level is essential. With this concept in mind, the second IWCN was held in Whistler Village in Canada in January 1993. Funding was generously provided by Schering AG, Berlin, and for the excellent organization we have to thank Ms. Ingeborg Runge.


cell mortality neurology pathology urology

Editors and affiliations

  • Yoshikuni Mizuno
    • 1
  • Donald B. Calne
    • 2
    • 3
  • R. Horowski
    • 4
  1. 1.Department of NeurologyJuntendo University School of MedicineHongo, Bunkyo, Tokyo 113Japan
  2. 2.Neurodegenerative Disorders CenterThe University of British ColumbiaVancouverCanada
  3. 3.Health Sciences CenterThe Vancouver HospitalVancouverCanada
  4. 4.Clinical Research, Special Research ProjectsSchering AG BerlinBerlin 65Germany

Bibliographic information