In Vivo Immunology

Histophysiology of the Lymphoid System

  • Paul Nieuwenhuis
  • A. A. van den Broek
  • M. G. HannaJr.

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Bone Marrow, B Cell Differentiation and the B Cell System

    1. Front Matter
      Pages 1-1
    2. Dennis G. Osmond
      Pages 3-10
    3. Paavo Toivanen, Olli Lassila, Jussi Eskola, Claude Martin, Francoise Dieterlen-Lievre, Douglas G. Gilmour
      Pages 11-17
    4. I. G. Barr, M. R. Alderton, J. L. Brumley, R. L. Boyd, H. K. Muller, H. A. Ward
      Pages 19-23
    5. L. Jaroskova, F. Kovaru, H. Tlaskalova, I. Trebichavsky, L. Fornusek, M. Holub
      Pages 25-30
    6. P. P. Le Bouteiller, G. L. Asherson
      Pages 31-38
    7. A. Chayen, S. Marshall-Clarke, R. M. E. Parkhouse
      Pages 53-59
    8. H. K. Forster, F. Suter, F. G. Gudat, J. P. Obrecht
      Pages 61-65
    9. D. S. Kumararatne, I. C. M. MacLennan, H. Bazin, D. Gray
      Pages 67-73
    10. D. S. Kumararatne, I. C. MacLennan
      Pages 83-90
    11. H. Snippe, B. Merchant, E. F. Lizzio, J. K. Inman
      Pages 91-96
    12. Olli Vainio, Olli Lassila, Auli Toivanen
      Pages 97-102
    13. J. J. Haaijman, W. J. A. Boersma
      Pages 103-109
    14. J. Rozing, L. M. B. Vaessen, L. Faber, M. van Oven, L. de Vries-Box, B. de Jong et al.
      Pages 111-118
  3. Lymphocyte Migration

    1. Front Matter
      Pages 137-137
    2. P. De Baetselier, E. Gorelik, Z. Eshhar, Y. Ron, S. Katsav, M. Feldman et al.
      Pages 179-185
    3. Gregory D. Carey, Yee-Hon Chin, Judith J. Woodruff
      Pages 187-192
    4. A. S. G. Curtis, R. M. Renshaw
      Pages 193-198
    5. Eugene C. Butcher, Georg Kraal, Susan K. Stevens, Irving L. Weissman
      Pages 199-206
    6. Reinhard Pabst, Ernst Nowara, Karla Potschick
      Pages 213-218
    7. Zlatko R. Angelov, Ludmilla A. Angelova
      Pages 225-233
  4. Thymus, T Cell Differentiation and the T Cell System

    1. Front Matter
      Pages 235-235
    2. W. van Ewijk, E. J. Jenkinson, P. L. van Soest, J. J. T. Owen
      Pages 241-248
    3. Jacques Boniver, Marie-Paule Houben-Defresne, Andree Varlet, Gerard Goffinet
      Pages 263-267
    4. Roland Scollay, Wei-Feng Chen, Graham Mitchell
      Pages 269-274
    5. Akira Kawaoi, Katsuyoshi Naito, Minoru Uchida, Kaeko Kamiya, Toshio Shikata
      Pages 275-280
    6. Francis Dumont, Robert C. Habbersett, Roger Barrois, Hubert Gerard
      Pages 297-302
    7. H. K. Muller-Hermelink, G. Steinmann, H. Stein
      Pages 303-312
    8. W. Leene, P. J. M. Roholl, K. A. Hoeben
      Pages 319-325
    9. J. Rozing, L. M. B. Vaessen, C. B. Carpenter, P. Joling
      Pages 327-333
    10. J. J. A. van Loon, C. J. Secombes, E. Egberts, W. B. van Muiswinkel
      Pages 335-341

About this book


In 1966, the first Germinal Centre Conference was held in Bern, Switzerland, as a result of an initiative from C. C. Longdon of Oak Ridge, Tennessee and H. Cottier of Bern. Fifteen years later, in June of 1981, the 7th conference in this series was held in Groningen, the Netherlands. At this "International Conference on Lymphatic Tissues and Germinal Centers in Immune Reactions," instead of focusing on germinal centres only, the intricate relationships between various constituents of the lympho-myeloid complex consti­ tuted the theme of the meeting. As Yoffee stated in 1966, "Perhaps we should consider not only the germinal centre itself but the surrounding tissue as well. " Over the years, these conferences have brought together a small but dedicated group of scientists, sharing (1) a fundamental interest in the physiology of the lymphoid system proper, and (2) the recognition that, only in the in vivo situation can the final answers be obtained, however ingeniously in vitro experiments may mimic reality. In 1966, the conference lasted three days and included 57 contributions "which were discussed at length. " The present conference accomodated 62 free papers and 64 poster presentations as well as some 24 additional abstracts selected from more than 200 submissions. Prominent among the selection criteria was the adage "in vivo veritas. " This volume represents the presentations from the 1981 Germinal Centre Conference.


T cell Thymus autoimmune disease blood histocompatibility immune response immune system immunity immunology infection leukemia lymphocytes physiology transplantation virus

Editors and affiliations

  • Paul Nieuwenhuis
    • 1
  • A. A. van den Broek
    • 1
  • M. G. HannaJr.
    • 2
  1. 1.University of GroningenGroningenThe Netherlands
  2. 2.NCI-Frederick Cancer Research FacilityFrederickUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1982
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-9068-8
  • Online ISBN 978-1-4684-9066-4
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site