Advances in Post-Translational Modifications of Proteins and Aging

  • Vincenzo Zappia
  • Patrizia Galletti
  • Raffaele Porta
  • Finn Wold

Part of the Advances in Experimental Medicine and Biology book series (NATO ASI F, volume 231)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Transglutaminase-Related Reactions

    1. Front Matter
      Pages N1-N1
    2. Soo I. Chung, Sung Keun Chang, Enzo T. Cocuzzi, J. E. Folk, Hee Chul Kim, Soo Young Lee et al.
      Pages 1-13
    3. Akitada Ichinose, Earl W. Davie
      Pages 15-27
    4. Janice A. Nagy, Richard L. Kradin, Jan McDonagh
      Pages 29-49
    5. R. H. Rice, R. Chakravarty, J. Chen, W. O’Callahan, A. L. Rubin
      Pages 51-61
    6. Peter J. A. Davies, E. Antonio Chiocca, Joseph P. Stein
      Pages 63-71
    7. W. W. de Jong, J. W. M. Mulders, C. E. M. Voorter, G. A. M. Berbers, W. A. Hoekman, H. Bloemendal
      Pages 95-108
    8. P. J. Birckbichler, L. E. Anderson, R. T. Dell’Orco
      Pages 109-117
    9. Anil B. Mukherjee, Eleonora Cordella-Miele, Tadahiro Kikukawa, Lucio Miele
      Pages 135-152
    10. S. Metafora, G. Peluso, G. Ravagnan, A. Fusco, V. Gentile, R. Porta
      Pages 175-184
    11. Mauro Piacentini, Maria Paola Ceru’-Argento, Maria Grazia Farrace, Francesco Autuori
      Pages 185-198
  3. Protein Methylation

About this book

Introduction

This volume contains 56 contributions presented at the 1st International Symposium on Post-Translational Modifications of Proteins and Ageing, held on the Island of Ischia (Naples, Italy) from May 11 to 15, 1987, under the auspices of the University of Naples and the Italian Society of Biochemistry. The primary aim of this interdisciplinary meeting was to promote a productive exchange among scientists from different cultural areas, and to give them the opportunity to discuss problems of common interest approached from different scientific standpoints. Although a large number of studies has led to a definition of the chemical mechanisms and of the main enzymological aspects of the several post-translational modifications of proteins, we are still far away from a complete elucidation of the functional significance of such processes. As a matter of fact, it seems reasonable that the presently available experi­ mental approaches and models employed to investigate the biological roles are still inadequate. The search for suitable model systems was a matter of discussion during the meeting, and will be a major challenge in the future. The most frequently employed approaches to this problem thus far have been in vitro, but several proteins reported to be excellent in vitro substrates failed to show any activity when assayed in in vivo models.

Keywords

biochemistry protein proteins translation

Editors and affiliations

  • Vincenzo Zappia
    • 1
  • Patrizia Galletti
    • 1
  • Raffaele Porta
    • 1
  • Finn Wold
    • 2
  1. 1.University of NaplesNaplesItaly
  2. 2.University of Texas Health Science CenterHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-9042-8
  • Copyright Information Springer Science+Business Media New York 1988
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-9044-2
  • Online ISBN 978-1-4684-9042-8
  • Series Print ISSN 0258-1248
  • About this book