Cortical Circuits

Synaptic Organization of the Cerebral Cortex Structure, Function, and Theory

  • Edward L. White

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Anatomy

    1. Front Matter
      Pages 1-3
    2. Edward L. White
      Pages 5-18
    3. Edward L. White
      Pages 19-45
    4. Back Matter
      Pages 83-105
  3. Functional Aspects of Cortical Circuitry

    1. Front Matter
      Pages 107-107
    2. Edward L. White
      Pages 109-131
    3. Edward L. White
      Pages 132-149
    4. Edward L. White
      Pages 150-158
    5. Back Matter
      Pages 159-176
  4. Facts, Theories, and Models

    1. Front Matter
      Pages 177-177
    2. Edward L. White
      Pages 179-206
    3. Back Matter
      Pages 207-215
  5. Back Matter
    Pages 217-223

About this book


This elegant book presents current evidence on the organization of the mammalian cerebral cortex. The focus on synapses and their function provides the basis for understanding how this critical part of the brain could work. Dr. White and his colleague Dr. Keller have collated an impressive mass of material. This makes the crucial information accessible and coherent. Dr. White pioneered an area of investigation that to most others, and occasionally to himself, seemed a bottomless pit of painstaking at­ tention to detail for the identification and enumeration of cortical syn­ apses. I do not recall that he or anyone else suspected, when he began to publish his now classic papers, that the work would be central to an accelerating convergence of information and ideas from neurobiology and computer science, especially artificial intelligence (AI) (Rumelhart and McClelland, 1986). The brain is the principal organ responsible for the adaptive capacities of animals. What has impressed students of biology, of medicine, and, to an extent, of philosophy is the correlation between the prominence of the cerebral cortex and the adaptive "complexity" of a particular spe­ cies. Most agree that the cortex is what sets Homo sapiens apart from other species quantitatively and qualitatively (Rakic, 1988). This is summarized in the first chapter.


anatomy biology cell medicine physiology science

Authors and affiliations

  • Edward L. White
    • 1
  1. 1.Department of Morphology, Corob Center for Medical SciencesBen Gurion University of the NegevBeer ShevaIsrael

Bibliographic information