Systems Approaches to Developmental Neurobiology

  • Pamela A. Raymond
  • Stephen S. EasterJr.
  • Giorgio M. Innocenti

Part of the NATO ASI Series book series (NSSA, volume 192)

Table of contents

  1. Front Matter
    Pages i-x
  2. Mar Ruiz-Gómez, Alain Ghysen
    Pages 11-19
  3. Fernando Jiménez, José A. Campos-Ortega
    Pages 21-27
  4. Janet E. Braisted, Pamela A. Raymond
    Pages 29-39
  5. Walter K. Metcalfe, Monte Westerfield
    Pages 41-47
  6. Linda S. Ross, Stephen S. Easter Jr.
    Pages 49-58
  7. Timothy Allsopp, Friedrich Bonhoeffer
    Pages 59-68
  8. J. S. H. Taylor, R. M. Gaze
    Pages 69-79
  9. Peter Kind, Giorgio Innocenti
    Pages 113-125
  10. Larry R. Stanford, S. Murry Sherman
    Pages 141-152
  11. Pamela A. Raymond, Stephen S. Easter Jr., Giorgio M. Innocenti
    Pages 167-182
  12. Back Matter
    Pages 183-194

About this book


It is appropriate at the outset of this book to pose a question that was often asked --of the organizers before the meeting took place and later among those who participated in the meeting -- "What is meant by 'Systems Approaches' in the study of developmental neurobiology?" The answer, as we originally conceived it, can be succinctly summarized by the word "interactions". That brief epithet was expanded during the general discussion portion of the meeting, where the following definition was offered: "Systems approaches in developmental neurobiology are unified by attention to the emergent properties of the developing system under investigation and by a focus on the aspects of development of the nervous system that depend on interactions among its various elements, be they molecular, intracellular or multicellular. " As opposed to ignoring complexity or trying to wish it away, those of us who utilize a systems approach embrace the principle that complexity is what makes the nervous system special. We have come to recognize that wherever we look, we find interactions which are to be probed and eventually. understood. Even the so-called "simple systems", a term that has been used to describe many invertebrate preparations, are embraced under the above definition, since with further study it is becoming increasing clear that such systems are not as simple as once thought. We also include molecular genetics under the systems rubric. After all, genes regulate other genes which regulate others, and so it goes.


Invertebrate Nervous System Vertebrate attention biology development genes neurobiology

Editors and affiliations

  • Pamela A. Raymond
    • 1
  • Stephen S. EasterJr.
    • 1
  • Giorgio M. Innocenti
    • 2
  1. 1.University of MichiganAnn ArborUSA
  2. 2.Institute of AnatomyLausanneSwitzerland

Bibliographic information