Gastrulation

Movements, Patterns and Molecules

  • Ray Keller
  • Wallis H. ClarkJr.
  • Frederick Griffin

Part of the Bodega Marine Laboratory Marine Science Series book series (BMSS)

Table of contents

  1. Front Matter
    Pages i-xii
  2. John Gerhart, Tabitha Doniach, Ronald Stewart
    Pages 57-77
  3. J. P. Trinkaus, Madeleine Trinkaus, Rachel D. Fink
    Pages 121-134
  4. Michael Weliky, George Oster
    Pages 135-146
  5. Rudolf Winklbauer, Andreas Selchow, Martina Nagel, Cornelia Stoltz, Brigitte Angres
    Pages 147-168
  6. Jean-Claude Boucaut, Thierry Darribère, De Li Shi, Jean-Francois Riou, Kurt E. Johnson, Michel Delarue
    Pages 169-184
  7. Douglas W. DeSimone, Jim C. Smith, James E. Howard, David G. Ransom, Karen Symes
    Pages 185-198
  8. Eric Wieschaus, Dari Sweeton, Michael Costa
    Pages 213-223
  9. Fred H. Wilt, Nikolaos C. George, Oded Khaner
    Pages 281-288

About this book

Introduction

Gastrulation is a fundamental process of early embryonic development. It involves virtually every aspect of cell and developmental biology and results in the formation of fundamental structural elements around which a developing animal's body plan is organized. As such it is not only an important process, but also one that is complicated and not easily dissected into its component parts. To understand the mechanisms of gastrulation one must acknowledge that gastrulation is fundamentally a biomechanical process (that is, a problem of cells generating forces in a three dimensional array, patterned in space and time such that appropriate tissue movements are executed). Three intertwined questions emerge: what cell activities generate forces, how are these cell activities patterned in space and time, and how are the resulting forces harnessed in three dimensional domains? To address these issues it is important to define and characterize regional cell behaviors and to learn how they are patterned in the egg and/ or by subsequent cell and tissue interactions. At the biochemical level, what are the cellular and extracellular molecules that control cell behavior? Finally, how are specific patterns of cellular activity integrated to produce tissue behavior? The task of answering the above questions, an immense task in itself, is compounded by the fact that the morphogenetic movements of gastrulation and their underlying mechanisms vary between different organisms.

Keywords

Gastrulation Mammalia Mesoderm Neurulation development developmental biology tissue

Editors and affiliations

  • Ray Keller
    • 1
  • Wallis H. ClarkJr.
    • 2
  • Frederick Griffin
    • 2
  1. 1.University of California, BerkeleyBerkeleyUSA
  2. 2.Bodega Marine LaboratoryUniversity of California, DavisBodega BayUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-6027-8
  • Copyright Information Springer-Verlag US 1991
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-6029-2
  • Online ISBN 978-1-4684-6027-8
  • About this book