Neuropathogenic Viruses and Immunity

  • Steven Specter
  • Mauro Bendinelli
  • Herman Friedman

Part of the Infectious Agents and Pathogenesis book series (IAPA)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Viruses and Neuropsychiatric Disorders

    1. Steven Specter, Mauro Bendinelli, Herman Friedman
      Pages 1-12
  3. General Information

    1. Front Matter
      Pages 13-13
    2. William R. Tyor, Richard T. Johnson
      Pages 15-39
    3. Michael C. Graves, Harry V. Vinters
      Pages 41-60
  4. Animal Models

    1. Front Matter
      Pages 61-61
    2. Gudmundur Pétursson, Ólafur S. Andrésson, Gudmundur Georgsson
      Pages 63-78
    3. Howard L. Lipton, Mauro C. dal Canto
      Pages 79-91
    4. Murray Gardner, Andrew Lackner, Linda Lowenstine
      Pages 93-109
    5. Richard I. Carp
      Pages 111-136
  5. Human Infections of the CNS

    1. Front Matter
      Pages 137-137
    2. Joseph L. Melnick
      Pages 139-153
    3. Anthony A. Nash, J. Matthias Löhr
      Pages 155-175
    4. Claes Örvell
      Pages 177-205
    5. Eugene O. Major, Dominick A. Vacante, Sidney A. Houff
      Pages 207-227
    6. Howard E. Gendelman, Seymour Gendelman
      Pages 229-254
    7. Diane E. Griffin
      Pages 255-274
  6. Perspectives

    1. Front Matter
      Pages 275-275
    2. H. E. Webb
      Pages 277-302
    3. Janice R. Stevens, Lesley M. Hallick
      Pages 303-316
    4. Anne M. Deatly, Ashley T. Haase, Melvyn J. Ball
      Pages 317-337
    5. Steven Specter, Mauro Bendinelli, Herman Friedman
      Pages 339-344
  7. Back Matter
    Pages 345-353

About this book


There has been a tremendous increase in interest in the neuropathogenicity of viruses during the past decade as we have come to recognize that the human immunodeficiency virus, which causes the acquired immunodeficiency syndrome (AIDS), can infect glial cells and cause neurological disease. Yet this increase has not been limited to AIDS but has extended to viruses that infect either or both the central and peripheral nervous systems. The changes examined here include both neurological and psychological diseases or syndromes. Moreover, the chapters in this volume review the interaction of the host immune system with the viruses examined and how such interactions may increase or decrease the neuropatho­ genicity of the viruses. Questions regarding viral neuropathogenesis include: (I) What is the mode of transmission of virus to the nervous system? (2) What types of cells are infected, and do they contain receptors for the virus? (3) What is the extent of damage that results from viral infection? (4) What are the immunologic mecha­ nisms by which damage is mediated or limited? Many of these questions remain unanswered, but this volume delves into efforts to provide some answers.


immune system immunodeficiency infection infections nervous system system virus

Editors and affiliations

  • Steven Specter
    • 1
  • Mauro Bendinelli
    • 2
  • Herman Friedman
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of South Florida, College of MedicineTampaUSA
  2. 2.Department of BiomedicineUniversity of PisaPisaItaly

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1992
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5888-6
  • Online ISBN 978-1-4684-5886-2
  • Series Print ISSN 1075-1289
  • Buy this book on publisher's site