New Experimental Modalities in the Control of Neoplasia

  • Prakash Chandra

Part of the NATO ASI Series book series (NSSA, volume 120)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Francois Gros, Marc Fiszman, Didier Montarras
    Pages 1-13
  3. Fritz Anders, Annerose Anders, Manfred Schartl, Thomas Gronau, Wolfgang Lüke, Carl-Rudolf Schmidt et al.
    Pages 15-40
  4. Patrick De Baetselier, Ed Roos, Hendrik Verschueren, Steven Verhaegen, Daniel Dekegel, Lea Brys et al.
    Pages 41-55
  5. Isaac P. Witz, Liora Agassy-Cahalon, Benjamin Fish, Yaron Lidor, Yardena Ovadia, Haim Pinkas et al.
    Pages 71-80
  6. L. Eisenbach, S. Katzav, M. Feldman
    Pages 81-90
  7. I. Keydar, I. Tsarfaty, N. Smorodinsky, E. Sahar, Y. Shoenfeld, S. Chaitchik
    Pages 123-135
  8. Marcelo B. Sztein, Allan L. Goldstein
    Pages 137-164
  9. Suresh K. Arya, M. G. Sarngadharan
    Pages 165-182
  10. J. R. Bertino, S. Srimatkandada, M. D. Carman, M. Jastreboff, L. Mehlman, W. D. Medina et al.
    Pages 183-193
  11. Thomas Grace, Yigal H. Ehrlich, Thomas R. Tritton
    Pages 195-202
  12. Ronald McCaffrey, Amy Ahrens, Richard Bell, Robert Duff, Henry Hoppe, Anne Lillquist et al.
    Pages 213-221
  13. R. Voegeli, J. Pohl, T. Reissmann, J. Stekar, P. Hilgard
    Pages 243-247

About this book


Acquisition of new knowledge about the biological and bio­ chemical nature of neoplastic cells has led to the design and development of several experimental approaches in the tre&tment of cancer. These approaches emerge from the recent work in tu­ mor virology, e. g. the control of vital cellular genes by viral regulatory signals; the implication of monoclonal antibodies as a vehicle for the targeted drug delivery and selective de­ struction of tumor cells; immunologic advances in the recog­ nition of some specific events during metastatic growth; the role of biological response modifiers in modifying or rever­ sing malignant growth; and biochemical advances, such as the role of gene amplification in drug resistance and the app­ roaches to the reversal of resistance in drug refractory cancer, the role of membranes in designing useful strategies, the identification of new enzymic targets in some types of cancer cells, and the characterization of metabolically active forms of cytostatic compounds. These are the important issues which were addressed in an international NATO Advanced Study Institute (ASI) attended by scientists from allover the world representing a wide spectrum of scientific disciplines. Although the acquired immune deficiency syndrome (AIDS) is not a malignant disease, but the etiological involvement of a retrovirus belonging to the family of human T-cell lympho­ tropic viruses which cause leukemia and lymphomas in man, justifies its inclusion in the agenda of this Study Institute. Scientific presentations from Drs.


AIDS biological biology cancer cell culture cells development experiment genes growth membrane molecular biology oncogene pharmacology protein

Editors and affiliations

  • Prakash Chandra
    • 1
  1. 1.University of FrankfurtFrankfurt am MainFederal Republic of Germany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1986
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5244-0
  • Online ISBN 978-1-4684-5242-6
  • About this book