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Table of contents

  1. Front Matter
    Pages i-xxi
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Edwin D. Kilbourne
      Pages 3-22
  3. The Influenza Viruses

    1. Front Matter
      Pages 23-23
    2. Edwin D. Kilbourne
      Pages 33-56
    3. Edwin D. Kilbourne
      Pages 57-87
  4. Influenza: Infection and Disease

    1. Front Matter
      Pages 155-155
    2. Edwin D. Kilbourne
      Pages 157-218
    3. Edwin D. Kilbourne
      Pages 219-228
    4. Edwin D. Kilbourne
      Pages 229-251
  5. Epidemiology, Surveillance, and Control

    1. Front Matter
      Pages 253-253
    2. Edwin D. Kilbourne
      Pages 255-289
    3. Edwin D. Kilbourne
      Pages 291-345
  6. Back Matter
    Pages 347-359

About this book

Introduction

My lifetime encompasses the postwar subsidence in the early 1920s of the greatest influenza pandemic in history, direct encounters with FM1 virus at Fort Mon­ mouth in 1947, the care of influenza patients in the 1950s, the pursuit of the in­ fluenza virus through the modern pandemics of 1957 and 1968, and a present in which the genes of the virus have dissembled in the DNA of vaccinia virus and Escherichia coli through the wand of "high tech. " If my corpus could be fossilized for archival and archaeological purposes, it would be found to contain immune cells branded with the imprint of the "swine" influenza virus of post-1918 and brain cells no less imprinted with memories of the abortive return of its descendant during America's bicentennial. But before that unlikely event, I wanted to try to make some sense out of this baffling dis­ ease and its viruses-expecting no definitive revelations but hoping for a sharper definition of problems. Hence this book. It is an audacious act in these days of specialization to essay a book such as this singlehandedly, but I have done so for selfish reasons. I wanted to reexam­ ine old questions about the nature of influenza and its epidemics in the light of the dazzling advances in molecular biology of the past few years. No virus has been better studied, but few diseases are less well understood.

Keywords

biology epidemics molecular biology pandemics virus

Authors and affiliations

  • Edwin D. Kilbourne
    • 1
  1. 1.Mount Sinai School of MedicineCity University of New YorkNew YorkUSA

Bibliographic information