Aging and Cell Structure

Volume 1

  • John E. JohnsonJr.

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Alan Peters, Deborah W. Vaughan
    Pages 1-34
  3. Peter S. Spencer, Jose Ochoa
    Pages 35-103
  4. Henryk M. Wisniewski, Raymond S. Sinatra, Khalid Iqbal, Inge Grundke-Iqbal
    Pages 105-142
  5. Angelos C. Economos, Jaime Miquel, Ralph C. Ballard, John E. Johnson Jr.
    Pages 187-214
  6. Warren Kline Bolton, Benjamin C. Sturgill
    Pages 215-250
  7. Edgar A. Tonna
    Pages 251-304
  8. Steven I. Baskin, Zebulon V. Kendrick, Jay Roberts, Robert J. Tomanek
    Pages 305-331
  9. S. A. Shafiq, S. Lewis, B. Leung, H. S. Schutta
    Pages 333-346
  10. Jaime Miquel, Angelos C. Economos, Klaus G. Bensch
    Pages 347-379
  11. Back Matter
    Pages 381-385

About this book


Approaching any task on aging brings a flood of images that are a personal repetition of what has been one of the greatest and most persistent concerns of mankind. Even restricting time to the past decade or so and approaching only the biomedical sciences, one still encounters a flood of information in this relatively young research area. The­ ories and ideas abound as though each researcher provides one of his own. This might well be expected; aging is an exceedingly complicated series of crossroads involving trails and even superhighways. Each specialist has a peephole (society, body, organ, tissue, cell, or-especially in modern biology-cellular organelles, macromolecules, and even molecules) and the views of the crossroads are obviously different. Hence, the num­ ber of observations just about equals the number of independent ideas put forward. It is natural to seek from highly specialized knowledge a fundamental understand­ ing of aging through the modern research trends in biology that focus on events at the cellular, subcellular, macromolecular, and molecular levels. The ultimate clues must lie there-with one serious complication: There are numerous cell types in any body and each cell type is a very complex machine of its own. Additionally, there are potential repercussions in that different cells, tissues, and even molecules have effects on one another. This is indeed a confusing situation, and one for which we must seek reliable answers, provided that we can take a step back and provide a generalized view.


RNA aging biology brain cell cells complication memory molecule organ protein research tissue

Editors and affiliations

  • John E. JohnsonJr.
    • 1
    • 2
  1. 1.Hitachi Scientific InstrumentsRockvilleUSA
  2. 2.National Institute on AgingNIH Baltimore City Hospital and Johns Hopkins University School of MedicineBaltimoreUSA

Bibliographic information