Pharmacology and Pharmacokinetics

  • Torsten Teorell
  • Robert L. Dedrick
  • Peter G. Condliffe

Table of contents

  1. Front Matter
    Pages i-xii
  2. G. Segre
    Pages 1-1
  3. Edward R. Garrett
    Pages 3-25
  4. John G. Wagner
    Pages 27-68
  5. S. Riegelman, M. Rowland
    Pages 87-103
  6. R. T. Williams
    Pages 105-115
  7. Robert L. Dedrick
    Pages 117-145
  8. A. H. Conney, B. Craver, R. Kuntzman, E. J. Pantuck
    Pages 147-162
  9. Bert N. La Du
    Pages 253-260
  10. Edward J. Goetzl, Shaun Ruddy, Daniel J. Stechschulte, K. Frank Austen
    Pages 281-296
  11. Malcolm Rowland
    Pages 321-337
  12. Kenneth B. Bischoff
    Pages 351-368
  13. Torsten Teorell
    Pages 369-371
  14. Back Matter
    Pages 373-388

About this book


This collection of papers by leading pharmacokineticists and pharmacolo­ gists is the proceedings of a conference held at the John E. · Fogarty International Center for Advanced Study in the Health Sciences, National Institutes of Health, October 30 to November 1, 1972. As part of its advanced study program, the Center conducts workshops, seminars, and conferences on topics related to the biomedical interests of the Scholars-in­ Residence. Professor Torsten Teorell came to the Center in 1970 as one of the first Scholars. In 1971 and 1972, he spent several months at the Center devoting his attention to contemporary problems in the application of pharmacoki­ netics to experimental and clinical pharmacology. As one of the founders of pharmacokinetics, Professor Teorell has made many contributions to the field since he first presented a formal multicompartment model for the analysis of drug action and drug metabolism in 1937 (Teorell, 1937). Since the appearance of his original paper, pharmacodynamics, or pharmacoki­ netics, has become increasingly important as a tool for the study of drug action in patients. The translation of experimental pharmacological findings into therapeutic regimens is today increasingly dependent on ade qua te models of drug action. The purpose of the conference, of which this book is the proceedings, was to discuss contemporary findings in this important biomedical research field. The conference program was designed by Professor Teorell with the help of a small committee which included Drs. Edward R.


drug kinetics metabolism pharmacodynamics pharmacokinetics research

Editors and affiliations

  • Torsten Teorell
    • 1
    • 2
  • Robert L. Dedrick
    • 3
  • Peter G. Condliffe
    • 4
  1. 1.Institute of Physiology and Medical BiophysicsUniversity of UppsalaUppsalaSweden
  2. 2.Fogarty International CenterNational Institutes of HealthBethesdaUSA
  3. 3.Biomedical Engineering and Instrumentation Branch Division of Research ServicesNational Institutes of HealthBethesdaUSA
  4. 4.Laboratory of Nutrition and EndocrinologyNational Institute of Arthritis, Metabolism, and Digestive Diseases National Institutes of HealthBethesdaUSA

Bibliographic information