Chromatin Structure and Function

Levels of Organization and Cell Function Part B

  • Claudio A. Nicolini

Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 21b)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Various Levels of Chromatin Organization and Mechanisms for Transcriptional Control

    1. Front Matter
      Pages 369-369
    2. N. M. Maraldi, S. Capitani, L. Cocco, F. A. Manzoli
      Pages 371-388
    3. K. E. Van Holde, J. R. Allen, J. Corden, D. Lohr, K. Tatchell, W. O. Weischet
      Pages 389-412
    4. K. Tatchell, K. E. Van Holde
      Pages 413-425
    5. Barbara Ramsay Shaw, Kenneth S. Schmitz
      Pages 427-440
    6. H. W. E. Rattle, G. G. Kneale, J. P. Baldwin, H. R. Matthews, C. Crane-Robinson, P. D. Cary et al.
      Pages 451-513
    7. Samarendra Basu
      Pages 515-540
    8. R. Stewart Gilmour
      Pages 561-591
  3. Structure-Function of the Genetic Apparatus and Cell Cycle, Aging, Neoplastic Transformation, Differentiation, Chemical Carcinogenesis

  4. Review and Summary of the Genetic Apparatus

    1. Front Matter
      Pages 847-848
    2. Claudio A. Nicolini
      Pages 849-854
    3. Claudio A. Nicolini
      Pages 855-859
    4. Claudio A. Nicolini
      Pages 861-865
    5. Claudio A. Nicolini
      Pages 867-870
  5. Back Matter
    Pages 871-880

About this book


This volume is the second part of the book on "Chromatin Structure and Function", which resulted from a NATO-Advanced Study Institute held at Erice during April 1978. In addition to giving an updated and detailed description of various levels of chromatin organization, i. e. octamers, nucleosomes, multimers, solenoid and higher order fibers (including the most recent, yet unpublished, findings), it focuses, in a tutorial and organic format, on the possible mechanisms controlling transcription and on the basic biological phenomena (either genetic or epigenetic) related to cell aging, cell cycle, differentiation, transformation and chemical carcinogenesis. The most significant (sometime spirite~ discussion sessions have been included at the end of every section. Their clarifying nature is further supported by the final section (V), which summarizes and reviews the current state of the art on the genetic apparatus and its constituents. All chapters have selected up-to-date references; quite a few have an extensive bibliography both in terms of basic reference books and most recent findings. A few chapters, dealing at the level of intact cell and/or in classical genetic terms, with aging, differentiation and neoplastic transformation, have been included to furnish a more comprehensive view of fundamental cell functions directly and indirectly related to the structure and function of the genetic apparatus. At the same time it is hoped that interested students and investigators will find in the chapters of this volume the necessary and stimulating introduction to the wide variety of fundamental mechanism and phenomena occurring in higher eukaryotes.


DNA aging biological cell cell cycle chromatin eukaryote eukaryotes nucleic acid protein structure transcription

Editors and affiliations

  • Claudio A. Nicolini
    • 1
  1. 1.Temple UniversityPhiladelphiaUSA

Bibliographic information