Central and Peripheral Mechanisms of Cardiovascular Regulation

  • A. Magro
  • W. Osswald
  • D. Reis
  • P. Vanhoutte

Part of the NATO ASI Series book series (NSSA, volume 109)

Table of contents

  1. Front Matter
    Pages i-x
  2. J. Verbist, G. Droogmans, F. Wuytack, R. Casteels
    Pages 33-58
  3. Michael J. Mulvany
    Pages 83-110
  4. Thomas C. Westfall, Shi-Qing Zhang, Suzanne Carpentier, Linda Naes, Michael J. Meldrum
    Pages 111-133
  5. P. M. Vanhoutte, D. S. Houston
    Pages 135-161
  6. Harvey R. Kaplan, Michael J. Ryan
    Pages 197-217
  7. Albert Magro, Nisan Gilboa, Ulrich Rudofsky
    Pages 219-267
  8. Lynne C. Weaver, Robert L. Meckler, Jean C. Tobey, Reuben D. Stein
    Pages 269-301
  9. Lawrence P. Schramm
    Pages 303-352
  10. M. Ian Phillips, Elaine M. Richards, Ahnke Van Eekelen
    Pages 385-441
  11. Michael J. Brody, Timothy P. O’Neill, James P. Porter
    Pages 443-464
  12. Luigi F. Agnati, Kjell Fuxe, Roberta Grimaldi, Anders Harfstrand, Michele Zoli, Isabella Zini et al.
    Pages 503-526
  13. Filippo Drago, Umberto Scapagnini
    Pages 527-536
  14. Back Matter
    Pages 537-544

About this book


There is increasing awareness that the autonomic nervous system, through its central and peripheral pathways, plays a critical role in the regulation of the circulation. Peripherally, the autonomic representation, largely that of sympathetic nerves, innervate virtually all segments of the vascular tree as well as the adrenal medulla. Through the interaction of nerve terminals, their transmitters, receptors and intracellular mediators in smooth muscle, sympathetic neurons control vascular tone as well as the basal performance of the heart. In turn, the performance of the autonomic nervous system is highly controlled by the brain. Once viewed as a black box with only a vague influence on cardiovascular performance, the introduction of concepts and techniques of neuroscience into the field of cardiovascular medicine has led to the realization of the critical role of this organ in cardiovascular control. It is now well recognized that within the brain, the represenation of cardiovascular function is highly restricted anatomically, engages a number of specific transmitters for its actions, and has highly selective and topographically restricted functions to influence circulatory performance.


Peptid brain circulation influence medicine nervous system neuroscience receptor receptors regulation smooth muscle system tree

Editors and affiliations

  • A. Magro
    • 1
  • W. Osswald
    • 2
  • D. Reis
    • 3
  • P. Vanhoutte
    • 4
  1. 1.Wadsworth Center for Laboratories and ResearchAlbanyUSA
  2. 2.University of PortoPortoPortugal
  3. 3.Cornell University Medical CollegeNew YorkUSA
  4. 4.Mayo Clinic and Mayo FoundationRochesterUSA

Bibliographic information