Hormones and Cancer

  • Wendell W. Leavitt

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 138)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Herbert W. Dickerman, S. Anand Kumar
    Pages 1-18
  3. Catherine B. Lazier, Susan A. Nadin-Davis, Alex Elbrecht, Marie-Luise Blue, David L. Williams
    Pages 19-38
  4. Wendell W. Leavitt, Rawden W. Evans, William J. Hendry III
    Pages 63-86
  5. David T. MacLaughlin, Paul E. Sylvan, George S. Richardson
    Pages 113-131
  6. Mara E. Lieberman, Richard A. Maurer, Philippa Claude, Julie Wiklund, Nancy Wertz, Jack Gorski
    Pages 151-163
  7. A. M. H. Brodie, H. J. Brodie, L. Romanoff, J. G. Williams, K. I. H. Williams, J. T. Wu
    Pages 179-190
  8. C. Longcope, T. Arunachalam, I. Rafkind, E. Caspi
    Pages 191-210
  9. Paul A. Kelly, Jean Djiane, Lucile Turcot-Lemay
    Pages 211-229
  10. Richard C. Moon, Rajendra G. Mehta
    Pages 231-249

About this book

Introduction

The papers in this volume were presented at the Symposium on Hormones and Cancer held March 24-26, 1980, at the Worcester Foundation for Experimental Biology, Shrewsbury, MA. The meeting was organized to review recent advances in basic and clinical research work on hormone-responsive tumors of the reproductive system. The association between protracted hormone action and cancer of the reproductive system is now irrefutable. Yet we still do not know how hormones initiate and promote neoplastic transformation of their target cells. A major effort is cur­ rently being directed at understanding the hormonal regulation of neoplastic cells, especially those arising from the breast, uterus, pituitary gland and prostate. The symposium brought together leading experts whose research is focused on this impor­ tant area of human health. Although many questions remain to be answered by future studies, the material covered in this volume provides an up-to-date overview of the current status of work in this area. The subjects range from the mechanism of hormone action to the treatment of hormone-dependent tumors, and topics include estrogen, progestin, androgen and glucocorticoid action~ hormone receptors~ specific protein responses~ developmental effects of estrogens and antiestrogens~ the DES syndrome~ regu­ lation of the cell cycle~ therapeutic effects of antiestrogens, aromatase inhibitors, iodoestrogens, progestins on estrogen­ dependent tumors~ characterization of retinoid-binding sites~ and the utility of various tumor markers.

Keywords

breast cancer cancer carcinoma cell endometrium etiology hormones liver tumor

Editors and affiliations

  • Wendell W. Leavitt
    • 1
  1. 1.Worcester Foundation for Experimental BiologyShrewsburyUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-7192-6
  • Copyright Information Springer-Verlag US 1982
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4615-7194-0
  • Online ISBN 978-1-4615-7192-6
  • Series Print ISSN 0065-2598
  • About this book