Heat Shock Proteins and the Cardiovascular System

  • A. A. Knowlton

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 192)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Wolfgang H. Dillmann, Ruben Mestril
    Pages 25-39
  3. Richard J. Heads, Derek M. Yellon
    Pages 41-69
  4. R. William Currie, J.-Christophe L. Plumier
    Pages 71-81
  5. Nikki J. Holbrook, Timothy W. Fawcett, Robert Udelsman
    Pages 99-110
  6. A. A. Knowlton, Masayuki Nakano, Douglas L. Mann
    Pages 111-126
  7. Hari S. Sharma, Joachim Stahl
    Pages 127-158
  8. Georg Schett, Bernhard Metzler, Albert Amberger, Dorothea Michaelis, Maria Romen, Qingbo Xu et al.
    Pages 183-196
  9. Back Matter
    Pages 227-231

About this book


Heat shock proteins (HSP) were originally described in heat-shocked drosophila by Ritossa in the early 1960's. In the last 5 years it has become apparent that these heat shock proteins have important functions both in the normal cell and in the stressed cell. These proteins constitute an endogenous protective system; mutations in the heat shock proteins can be lethal, and there are no known organisms without heat shock proteins. The first observations on heat shock proteins and the heart were made in the 1980's and interest in these proteins increased over the decade. In the last few years there has been an exponential growth in number of papers published on heat shock proteins and the heart. Heat shock proteins have been implicated in a number of cardiovascular research areas including ischemia, hypertrophy, aging, and atherosclerosis, and this list is growmg. The purpose of this volume is to give an overview of our current understanding of the heat shock proteins in the cardiovascular system, and to summarize the approaches to the study of heat shock proteins in the heart. This volume assembles results from a number of different cardiovascular fields. and provides a comprehensive review of heat shock proteins in the cardiovascular system.


atherosclerosis cardiovascular cardiovascular system heart

Editors and affiliations

  • A. A. Knowlton
    • 1
    • 2
  1. 1.Cardiology Section, Department of MedicineV.A. Medical Center and Baylor College of MedicineHoustonUSA
  2. 2.Baylor College of MedicineHoustonUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1997
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7832-7
  • Online ISBN 978-1-4615-6177-4
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site