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The Fate of the Male Germ Cell

  • Book
  • © 1997

Overview

Editors:
  1. Richard Ivell

    1. Institute for Hormone and Fertility Research, University of Hamburg, Hamburg, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Adolf-Friedrich Holstein

    1. Anatomical Institute, University of Hamburg, Hamburg, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 424)

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Table of contents (54 chapters)

  1. The Role of the Testicular Accessory Cells

    1. Protease-Protease Inhibitor Interactions in Sertoli Cell-Germ Cell Crosstalk

      • T. K. Monsees, W. B. Schill, W. Miska
      Pages 111-123

    2. New Aspects of Leydig Cell Function

      • R. Middendorff, D. Müller, H. J. Paust, A. F. Holstein, M. S. Davidoff
      Pages 125-138

    3. Sertoli Cell-Specific Gene Expression in Conditionally Immortalized Cell Lines

      • N. Walther, M. Jansen, S. Ergün, B. Kascheike, G. Tillmann, R. Ivell
      Pages 139-142

    4. Functional Markers for Fetal and Postnatal Differentiation of Rat Leydig Cells

      • S. G. Haider, G. Servos, S. Tajtaraghi, G. Berthold, A. K. Mukhopadhyay, N. Kilic et al.
      Pages 143-144

    5. Enzyme Histochemical Addition to Morphological Features of Leydig Cells in Senium

      • D. Passia, B. Hilscher
      Pages 145-146

    6. Differential Display PCR Cloning of W/Wv-Mutant Testis Specific Genes

      • C. Hansis, D. Jähner, A.-N. Spiess, R. Ivell
      Pages 147-149

    7. Immunoreactivity for Glial Cell Markers in the Human Testis

      • M. S. Davidoff, R. Middendorff, D. Müller, E. Köfüncü, A. F. Holstein
      Pages 151-152

    8. Insulin-Like Growth Factor-Binding Protein (IGFBP)-5 in Human Testicular Tubules

      • B. Drescher, W. Zumkeller, H. Lauke, M. Hartmann, M. S. Davidoff
      Pages 153-154

    9. A Novel Role for Atrial Natriuretic Peptide (ANP) in Testis

      • D. Müller, R. Middendorff
      Pages 155-156

    10. Nerve Growth Factor (NGF) Receptors in Male Reproductive Organs

      • D. Müller, H.-J. Paust, R. Middendorff, M. S. Davidoff
      Pages 157-158

    11. Delayed Onset of Spermatid Elongation on the Pubertal Golden Hamster Testis Depends on a Developmental Deficiency of Leydig Cell-11ß-HSD

      • A. Miething
      Pages 159-160

  2. Compartmentalization, Vascularization, and Angiogenesis

    1. Compartmentalization of the Intertubular Space in the Human Testis

      • A. F. Holstein, M. Davidoff
      Pages 161-162

    2. Microcirculation and the Vascular Control of the Testis

      • S. Ergün, N. Kilic, S. Harneit, H. J. Paust, H. Ungefroren, A. Mukhopadhyay et al.
      Pages 163-180

    3. Expression of VEGF and its Receptors and Capillary Density in Leydig Cell Tumors of the Human Testis

      • N. Kilic, W. Fiedler, A. F. Holstein, S. Ergün
      Pages 181-182

    4. Angioarchitecture of the Human Spermatic Cord

      • S. Ergün, T. Bruns, R. Tauber
      Pages 183-184

    5. Morphological and Functional Aspects of the Human Spermatic Cord Veins

      • T. Bruns, R. Tauber, S. Ergün
      Pages 185-186

    6. Semen Analysis after Treatment of Varicocele by Antegrade Scrotal Sclerotherapy

      • N. Johnsen, R. Tauber, I. Johnsen
      Pages 187-188

    7. VEGF Modulates the Capillaries of the Human Epididymis

      • S. Ergün, W. Empen, W. Fiedler
      Pages 189-190

    8. Endothelin-1 and Its Receptors in the Human Epididymis

      • S. Harneit, S. Ergün, A. F. Holstein, H.-J. Paust, A. K. Mukhopadhyay
      Pages 191-192

  3. Post-Testicular Sperm Maturation

    1. The Role of Apocrine Released Proteins in the Post-Testicular Regulation of Human Sperm Function

      • G. Aumüller, H. Renneberg, P.-J. Schiemann, B. Wilhelm, J. Seitz, L. Konrad et al.
      Pages 193-219
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Keywords

About this book

THE FASCINATION The male germ cell is the only cell of the human organism that leaves the body when it has achieved its final, highly sophisticated structure and properties. The male germ cell is designed for one purpose only: to reach the female gametes and to fertilize them. The various stages in the development of the male germ cell are characterized by proliferative phases, by the recombination of the maternal and paternal chromosomes, and by the differentiation and development of a specialized transport vehicle, the spermato­ zoon. Furthermore, the establishment of a special pool of stem cells, the spermatogonia, guarantees the continuity of the sperm-generation process from puberty to old age. THE FATE OF THE MALE GERM CELL The destiny of any individual germ cell is determined by a program that we know only in fragments. On the one hand every human male is able to produce many billions of germ cells in his lifetime, yet the chance of any single sperm reaching and fertilizing the female germ cell is exceedingly rare. A fertility disturbance means that somewhere during the complicated playing out of the germ cell program mistakes are made, and the program fails. It is still a fact that more than 50% of men presenting with male factor infertility have to be diagnosed as idiopathic, largely because of our lack of knowledge and conse­ quent lack of appropriate diagnostic tools.

Editors and Affiliations

  • Institute for Hormone and Fertility Research, University of Hamburg, Hamburg, Germany

    Richard Ivell

  • Anatomical Institute, University of Hamburg, Hamburg, Germany

    Adolf-Friedrich Holstein

Bibliographic Information

  • Book Title: The Fate of the Male Germ Cell

  • Editors: Richard Ivell, Adolf-Friedrich Holstein

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-5913-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1997

  • Hardcover ISBN: 978-0-306-45696-1Published: 31 October 1997

  • Softcover ISBN: 978-1-4613-7711-5Published: 28 October 2012

  • eBook ISBN: 978-1-4615-5913-9Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XV, 332

  • Topics: Human Genetics, Veterinary Medicine/Veterinary Science

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