Metals and Genetics

  • Bibudhendra Sarkar

Table of contents

  1. Front Matter
    Pages i-xi
  2. William A. Suk
    Pages 1-3
  3. Chun Xu, Barry P. Rosen
    Pages 5-19
  4. R. Nilsson, A. T. Natarajan, A. Hartwig, F. Dulout, M. E. De la Rosa, M. Vahter
    Pages 21-40
  5. Badal K. Mandai, Bhaja K. Biswas, Ratan K. Dhar, Tarit Roy Chowdhury, Gautam Samanta, Gautam K. Basu et al.
    Pages 41-65
  6. Seth H. Frisbie, Donald M. Maynard, Bilqis A. Hoque
    Pages 67-85
  7. Andreas Kortenkamp
    Pages 87-100
  8. Horacio Kido, Ferenc Szurdoki, Mae S. Gustin, Bruce D. Hammock
    Pages 101-116
  9. Maria C. Linder, Stephanie Donley, David Dominguez, Lisa Wooten, Farrokh Mehrbod, Philip Cerveza et al.
    Pages 117-129
  10. Konstantin Salnikow, Daoji Zhou, Tomasz Kluz, Cheng Wang, Max Costa
    Pages 131-144
  11. Detmar Beyersmann, Carsten Schmidt
    Pages 145-158
  12. Andrea Hartwig, Leon H. F. Mullenders, Monika Asmuß, Maike Benters, Ines Krüger
    Pages 159-169
  13. Lucy M. Anderson, Marek A. Sipowicz, Wei Yu, Bhalchandra A. Diwan, Lisa Birely, Diana C. Haines et al.
    Pages 171-182
  14. Robyn P. Hickerson, Victor Duarte, J. David Van Horn, Ronelito J. Perez, James G. Muller, Steven E. Rokita et al.
    Pages 183-196
  15. David S. Sigman, Lisa Milne, Yue Xu, James Gallagher, David M. Perrin, Clark Pan
    Pages 197-208
  16. J. Koropatnick, J. M. De Moor, O. M. Collins
    Pages 209-220
  17. Jerry Kaplan, Derek Radisky, Michael Babcock
    Pages 229-236
  18. D. M. Glerum, J. Beers, A. Tzagoloff, F. Punter, D. Adams
    Pages 237-254
  19. Diane W. Cox, John R. Forbes, Manoj S. Nanji
    Pages 255-264
  20. Zeynep Tümer, Nina Horn
    Pages 279-290
  21. Daniel Strausak, Loreta Ambrosini, Julian F. B. Mercer
    Pages 291-300
  22. David Eide, Hui Zhao, Edward Butler, Jacquelyn Rodgers
    Pages 325-338
  23. Peter Lichtlen, Çagatay Günes, Rainer Heuchel, Oleg Georgiev, Karl-Heinz Müller, Horst Blüthmann et al.
    Pages 339-352
  24. Valeria Cizewski Culotta, Xiu Fen Liu, Paul Schmidt
    Pages 353-363
  25. Robert A. Pufahl, Thomas V. O’Halloran
    Pages 365-374
  26. R. Faraonio, P. Moffatt, O. LaRochelle, R. Saint-Arnaud, C. Séguin
    Pages 375-390
  27. Back Matter
    Pages 391-396

About this book


During the past few years, major scientific discoveries have greatly contributed to our understanding of the relationship between metals and genetics. The fields which have contrib­ uted to this area range from Clinical Medicine and Genetics to Biochemistry and Chemistry. The aim of this book is to bring together investigators from these diverse fields to reflect on the broad implications of direct and indirect interactions of metals and genetic components. The volume begins with a tribute to the late Karen Wetterhahn, an outstanding scien­ tist in the field, who will be sadly missed by her friends and colleagues because of her un­ timely death. The book has 28 chapters contributed by scientists who are internationally known for their expertise and outstanding research. The subject matters are divided into five major sections. The first section discusses genetic response to environmental expo­ sure to metals. Potentially devastating health crises have been reported in recent years from several parts of the world, which stem from environmental exposure to metals. In this section, authors report their findings on the effects and influence of metals in gene ex­ pression and their consequences to human health. The section on metal carcinogenesis and metal caused DNA damage, presents the latest advances in our knowledge of the molecu­ lar mechanisms of metal-induced mutagenesis and carcinogenesis. This topic is at the very heart of our understanding of how cancer may be caused by various metals.


DNA biochemistry gene expression genes genetics molecular mechanisms pathophysiology physiology regulation

Editors and affiliations

  • Bibudhendra Sarkar
    • 1
  1. 1.The Hospital for Sick ChildrenThe University of TorontoTorontoCanada

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic/Plenum Publishers 1999
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7140-3
  • Online ISBN 978-1-4615-4723-5
  • Buy this book on publisher's site