Cell and Molecular Biology of the Ear

  • David J. Lim

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Mechanoreceptor Biology

    1. Front Matter
      Pages 1-1
    2. Glen M. Watson, Patricia Mire
      Pages 19-39
    3. Rachel A. Dumont, Peter G. Gillespie
      Pages 41-54
  3. Developmental Biology of the Ear

    1. Front Matter
      Pages 85-85
    2. Clare V. H. Baker, Andrew K. Groves, Michael R. Stark, Marianne Bronner-Fraser
      Pages 87-97
    3. Donna M. Fekete, Xiaoying Gao
      Pages 99-112
  4. Genes and Deafness

  5. Gene-Based Therapy for Sensorineural Hearing Loss

    1. Front Matter
      Pages 215-215
    2. Yehoash Raphael
      Pages 217-223
    3. Anil K. Lalwani, Jayne A. Goldstein, Anand N. Mhatre
      Pages 225-237
    4. H. Staecker, W. Liu, H. Stupak, P. Lefebvre, M. Halterman, B. Malgrange et al.
      Pages 239-257
  6. Back Matter
    Pages 259-267

About this book


Dr. Howard House, founder of the House Ear Institute and House Ear Clinic often uses the analogy of planting a seed when referring to establishing the House Ear Institute in 1946. Two grateful patients of Dr. House put forth the idea that his knowledge and innovative skills could be used to expand the understanding of hearing impairment and its treatment. Those two early patients provided the "seed money" to begin the Institute. Since that time, the growth has been phenomenal­ from a one-man laboratory to a multidisciplinary facility boasting over 175 scien­ tists, physicians, and support staff, all dedicated to the advancement of otologic research and education. Six years ago after a half-century of remarkable success with prosthetic and device research, the Institute began cultivating a new field of endeavor-cell and molecular biology. Don Nielsen, then the Institute's Executive Vice President for Research and Scientific Director, began exploring the potential for hair cell regen­ eration and presented his ideas to the Board of Trustees. For a period of six months, we did a lot of fact finding to assess what role the Institute might take in this excit­ ing new field.


ATPase cells gene therapy gene transfer genes genetics molecular biology

Editors and affiliations

  • David J. Lim
    • 1
  1. 1.House Ear InstituteLos AngelesUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2000
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6896-0
  • Online ISBN 978-1-4615-4223-0
  • Buy this book on publisher's site