Cardiac Dysfunction in Chronic Uremia

  • Patrick S. Parfrey
  • John D. Harnett

Part of the Topics in Renal Medicine book series (TIRM, volume 10)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Epidemiology

    1. Front Matter
      Pages 1-1
    2. Philip J. Held, Nathan W. Levin, Friedrich K. Port
      Pages 3-17
    3. Robert N. Foley, Patrick S. Parfrey
      Pages 19-38
    4. Patrick S. Parfrey, John D. Harnett
      Pages 39-51
  3. Pathogenesis

    1. Front Matter
      Pages 83-83
    2. Grover M. Hutchins
      Pages 85-104
    3. Rainer Nowack, Alexander P. Mandelbaum, Eberhard Ritz
      Pages 105-115
    4. Shaul G. Massry, Miroslaw Smogorzewski, Alessandra F. Perna
      Pages 139-160
    5. Allan D. Sniderman, Jonathan Silberberg, Sarah Prichard, Paul E. Barré
      Pages 161-170
    6. Biff F. Palmer, William L. Henrich
      Pages 171-185
    7. R. Jean Shapiro
      Pages 187-204
    8. Leif Thuesen, Jens Sandahl Christiansen, Carl Erik Mogensen
      Pages 205-217
  4. Management

    1. Front Matter
      Pages 219-219
    2. John D. Harnett, Patrick S. Parfrey
      Pages 221-229
    3. Louise F. Roy, Frans H. H. Leenen
      Pages 247-266
    4. Suzanne K. Swan, William M. Bennett
      Pages 267-282
    5. M. Henry Gault, Brendan J. Barrett
      Pages 283-302
  5. Back Matter
    Pages 303-318

About this book


Cardiac disease is the major cause of death in dialysis patients, accounting for over one third of deaths. This book focuses on myocardial function and dysfunction in chronic uremia. It is aimed at practicing and training nephrologists, cardiologists, and internists, and at research workers in the field. We have tried to produce an up-to-date, in-depth review of the subject by inviting experts in clinical epidemiology, pathophysiology, and thera­ peutics to write the 18 chapters. The book is divided into three sections. The first section comprises five chapters that provide an overview of the burden of illness associated with cardiac disease in end-stage renal disease and a review of clinical epidemi­ ological aspects of various cardiac diseases that occur in renal patients. The second section discusses abnormalities of left ventricular contractility and mass, and the factors that predispose to both systolic and diastolic disorders. The importance of hypertension, anemia, hyperparathyroidism, hyper­ lipidemia, and diabetes mellitus in predisposing to these abnormalities is reviewed splendidly by researchers active in these areas. The final section concentrates on therapeutics. Data and opinion on management of congestive heart failure, cardiomyopathy, coronary artery disease, hypertension, and arrhythmias are provided. In editing this book, we have reviewed an extensive literature, but un­ fortunately we have become more aware that substantial gaps in our knowl­ edge exist. Insufficient high-quality clinical research has been undertaken xiii xiv Preface regarding the various cardiac diseases that occur in end-stage renal disease.


arrhythmia cardiovascular coronary artery disease coronary heart disease dialysis drugs heart heart disease heart failure hypertension physiology

Editors and affiliations

  • Patrick S. Parfrey
    • 1
  • John D. Harnett
    • 1
  1. 1.The Health Sciences CentreMemorial University of NewfoundlandSt. John’sCanada

Bibliographic information