Breast Cancer: Biological and Clinical Progress

Proceedings of the Conference of the International Association for Breast Cancer Research, St. Vincent, Aosta Valley, Italy, May 26–29, 1991

  • Editors
  • L. Dogliotti
  • A. Sapino
  • G. Bussolati

Part of the Developments in Oncology book series (DION, volume 69)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Activation of Cellular Oncogenes

    1. Front Matter
      Pages 1-1
    2. M. F. Di Renzo, M. Prat, M. Olivero, T. Crepaldi, P. M. Comoglio
      Pages 11-21
    3. Robert D. Cardiff, David Ornitz, Frederick Lee, Randall Moreadith, Eric Sinn, William Muller et al.
      Pages 41-55
  3. Polypeptides and Growth Factors Expression

  4. Mammary Epithelium and Stroma in Vivo and in Vitro

    1. Front Matter
      Pages 103-103
    2. J. Russo, G. Calaf, J. Ochieng, I. H. Russo, Q. Tahin, P.-L. Zhang
      Pages 105-117
    3. I. Vlodavsky, R. Ishai-Michaeli, M. Mohsen, G. Korner, R. Catane
      Pages 137-150
  5. Hormone Responsiveness and Oral Contraceptives

    1. Front Matter
      Pages 151-151
    2. Saverio Bettuzzi, Alan Robinson, Robin Fuchs-Young, Geoffrey L. Greene
      Pages 153-167
  6. Risk Factors; Monitoring of Breast Cancer Progression and Regression

    1. Front Matter
      Pages 179-179
    2. David L. Page, William D. Dupont
      Pages 181-193
    3. A. Sapino, L. Macrì, P. Gugliotta, C. Manini, G. Bussolati
      Pages 195-206
    4. D. Medina, R. Mukhopadhyay, M. Bansal
      Pages 225-232
  7. Biological Factors of Prognosis; The Metastatic Phenotype

    1. Front Matter
      Pages 233-233
    2. Marcel Garcia, Françoise Capony, Henri Rochefort
      Pages 243-253
    3. A. Schauer, D. Marx, I. Lipp, M. Schumacher, W. Sauerbrei, H. Rauschecker et al.
      Pages 255-276
  8. Therapeutic Strategies in Breast Cancer Treatment

    1. Front Matter
      Pages 277-277
    2. J. G. M. Klijn, P. M. J. J. Berns, M. Bontenbal, J. Alexieva-Figusch, J. A. Foekens
      Pages 301-311

About this book


The fight against breast cancer is expected to be effectively stimulated by interdisciplinary approaches and cross-fertilization between laboratory and clinical research findings. Of major importance are therefore meetings promoting fast transfer to clinical applications of findings by basic scientists. The present volume, reporting the proceedings of the 1991 Biennial Conference of the International Association for Breast Cancer Research, hopes to achieve this goal by presenting the most recent observations in the laboratory and their possible applications for diagnostic evaluations and clinical treatments. The sections of the book focus first on the oncogenes more likely involved in mammary tumorigenesis and on the polypeptide factors and steroid hormones affecting proliferation and possibly inducing carcinogenesis in breast epithelium. A section is devoted to the epidemiological studies and to the identification of risk factors, a way to select populations at higher risk and, possibly, to help in preventing the disease. Special emphasis is given to the establishment of diagnostic criteria and to the selection of prognostic factors, which must support an effective therapeutic planning. It is our hope that this volume, a timely update of the most recent advances in specific fields presented by basic scientists, pathologists and clinicians will stimulate new insights and progresses leading ultimately to the control of breast cancer.


cancer treatment carcinogenesis cell hormones metastasis oncogene tumor tumor progression tumorigenesis

Bibliographic information