Combination Therapies 2

Biological Response Modifiers in the Treatment of Cancer and Infectious Diseases

  • Enrico Garaci
  • Allan L. Goldstein

Table of contents

  1. Front Matter
    Pages i-x
  2. Mechanism of Action and Rationale for the Use of Biological Response Modifiers, Differentiating Agents and Nucleoside Analogues in Combination

    1. John W. Hadden, Piotr Malec, Anutosh Saha, Elba M. Hadden
      Pages 1-10
    2. Jeffrey L. Rossio, Helen C. Rager, Carol S. Goundry, Walter J. Urba
      Pages 11-21
    3. Alexander Fefer, Mark C. Benyunes, Carl Higuchi, Andrea York, Celso Massumoto, Catherine G. Lindgren et al.
      Pages 23-29
    4. Federica Cavallo, Francesco Di Pierro, Mirella Giovarelli, Alessandra Vacca, Alberto Gulino, Antonella Soppacciaro et al.
      Pages 31-37
    5. Enrico Garaci, Antonio Mastino, Francesca Pica, Cartesio Favalli
      Pages 49-60
    6. Giampietro Ravagnan, Roberto Falchetti, Paolo Di Francesco, Roberta Gaziano, Giulia Lanzilli, Cartesio Favalli et al.
      Pages 61-66
    7. Santo Landolfo, Marisa Gariglio, Mirella Gaboli, David Lembo, Cristina Mana, Paola Foresta et al.
      Pages 67-70
    8. Ildo Nicoletti, Graziella Migliorati, M. Cristina Pagliacci, Fausto Grignani, Carlo Riccardi
      Pages 71-79
    9. Alberto Mantovani, Barbara Bottazzi, Silvano Sozzani, Giuseppe Peri, Paola Allavena, Annunciata Vecchi et al.
      Pages 87-94
    10. Giancarlo Palmieri, Giuseppe Nicoletti, Silvia Cantoni, Lucio Bucci
      Pages 95-103
    11. Vito M. Fazio, Giuseppina Barrera, Roberto Muraca, Monica Rinaldi, Silvia A. Ciafrè, Marzia Lazzari et al.
      Pages 105-114
    12. C. F. Perno, V. Del Gobbo, J. Balzarini, E. Balestra, G. Milanese, S. Aquaro et al.
      Pages 115-122
    13. Klaus Bendtzen, Morten B. Hansen, Morten Svenson
      Pages 123-134
  3. Combination Chemotherapy and BRM Therapy in the Treatment of Cancer

    1. Grazia Graziani, Stefania D’Atri, Anna Giuliani, Annibale Franchi, Daniela Piccioni, Giuseppe Papa et al.
      Pages 135-147
    2. Massimo Lopez, Giovanni Bonsignore, Modesto D’Aprile, Cartesio Favalli, Marina Della Giulia, Luigi Di Lauro et al.
      Pages 149-153
    3. Peeyush K. Lala, Nahla Al-Mutter, Ranjit Parhar, Mary Nel Saarloos, Vivien Bramwell, William C. Mertens et al.
      Pages 155-165
    4. G. Sergio Del Giacco, Giovanni Mantovani, Paola Lai, Emiliano Turnu, Francesca Locci, Anna Carla Scanu et al.
      Pages 167-170
    5. Adriano Venditti, Maria Teresa Scimo, Giovanni Del Poeta, Roberto Stasi, Ugo Coppetelli, Mario Masi et al.
      Pages 171-177
    6. Anna Butturini, Robert Peter Gale
      Pages 179-187
  4. Single and Combination Therapy with BRM’s in the Treatment of Infectious Diseases, AIDS and Autoimmunity

    1. Paolo Di Francesco, Roberta Gaziano, Francesca Pica, Ida Casalinuovo, Anna Teresa Palamara, Luisella Belogi et al.
      Pages 189-194
    2. Luigina Romani, Elio Cenci, Antonella Mencacci, Roberta Spaccapelo, Enrico Schiaffella, Laura Tonnetti et al.
      Pages 195-200
    3. Chang Xue Zheng, Cheng Su Xu, Shilian Liu
      Pages 201-208
    4. Milton G. Mutchnick, J. I. Jaurequi, David A. Shafritz
      Pages 217-223
    5. Thomas C. Merigan
      Pages 225-228
    6. F. Aiuti, E. Scala, I. Mezzaroma, G. P. D’Offizi, R. Ferrara, G. Ricci et al.
      Pages 229-233
    7. Enrico Garaci, Giovanni Rocchi, Luigi Perroni, Cartesio D’Agostini, Fabrizio Soscia, Antonio Mastino et al.
      Pages 235-242
    8. Ladislav Borecky, Vladimír Lackovic, Peter Kontsek, Norbert Fuchsberger, Miroslav Kubes, Jozef Rovensky
      Pages 243-249
  5. Back Matter
    Pages 251-256

About this book


The 2nd International Symposium on Combination Therapies brought together several hundred of the leading researchers, scientists and clinicians in this area to discuss new and emerging uses for biological response modifiers (BRM's) in the treatment of cancer and infectious diseases. The meeting was held during May 1-3, 1992 in Acireale, Sicily (Italy). It was hosted by Professor G. Nicoletti CU. of Catania) and organized by the Institute for Advanced Studies in Immunology and Aging (Washington, D. C. ) in collaboration with the University of Rome "Tor Vergata," the University of Catania and The George Washington University Medical Center. The synergy exhibited between BRM's and conventional therapies including bone marrow and other lymphoid cell transplants is a rapidly expanding area with significant promise for the treatment of human diseases. Advances in this area of biomedicine are leading to the rapid development of new therapeutic approaches that are being applied clinically as both primary and adjuvant therapy to enhance the effectiveness of conventional treatments. The 2nd International Symposium on Combination Therapy provided a setting for the exchange of new scientific information regarding the emerging uses for BRM's alone or in combination with conventional therapies. The 1st International Symposium on Combination Therapies was held in 1991 in Washington, D. C.


AIDS autoimmunity biomedicine cancer chemotherapy cytokine diseases immunotherapy infectious infectious disease infectious diseases research

Editors and affiliations

  • Enrico Garaci
    • 1
  • Allan L. Goldstein
    • 2
  1. 1.University of Rome “Tor Vergata”RomeItaly
  2. 2.The Institute for Advanced Studies in Immunology and AgingUSA

Bibliographic information