Head and Neck Cancer

Basic and Clinical Aspects

  • Waun Ki Hong
  • Randal S. Weber

Part of the Cancer Treatment and Research book series (CTAR, volume 74)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Dong M. Shin, Michael A. Tainsky
    Pages 17-42
  3. Reuben M. Lotan
    Pages 43-72
  4. Margaret R. Spitz
    Pages 73-87
  5. Scott M. Lippman, Gary L. Clayman, Martin H. Huber, Steven E. Benner, Waun Ki Hong
    Pages 89-115
  6. Douglas D. Boyd, Garth L. Nicolson
    Pages 117-130
  7. Ralph R. Weichselbaum, Michael A. Beckett, Everett E. Vokes, David G. Brachman, Daniel Haraf, Dennis Hallahan et al.
    Pages 131-140
  8. Jack L. Gluckman, Robert P. Zitsch
    Pages 141-157
  9. Jack L. Gluckman, Louis G. Portugal
    Pages 159-171
  10. Daniel J. Haraf, Ralph R. Weichselbaum, Everett E. Vokes
    Pages 173-198
  11. Charles R. Dibb, Susan Urba, Gregory T. Wolf
    Pages 199-219
  12. Arlene A. Forastiere, Susan G. Urba
    Pages 263-281
  13. Helmuth Goepfert
    Pages 283-292
  14. Back Matter
    Pages 293-304

About this book

Introduction

Throughout the world, head and neck cancer is a major threat to public health and a significant challenge to both clinicians and basic scientists. Despite extensive efforts in primary prevention, screening, early detection, and therapy, long-term survival rates have not improved substantially in the last three decades. This book covers a wide range of exciting new findings in both clinical and basic sciences as they are relevant to head and neck cancer. These findings have recently enhanced our understanding of head and neck carcinogenesis at the genetic and molecular levels, offering the promise of improved preventive and therapeutic strategies. This book will also present information on the important clinical advances that have been made in chemoprevention, organ preservation, and the simultaneous use of chemo­ therapy and radiotherapy. The first part provides an overview of the etiology and biology of head and neck cancer, including an examination of human papillomaviruses in both benign and malignant lesions. This section also discusses the carcinogenic process at the genetic and molecular levels, as well as aberrant squamous differentiation; increased understanding of these areas has great potential to translate into new strategies for cancer prevention. The second part describes recent advances in developing a risk model for head and neck cancer, as well as the application of genetic susceptibility data in chemoprevention. This section also includes overviews of the status of chemoprevention trials and of the process of invasion and metastasis in head and neck cancer.

Keywords

adjuvant therapy cancer cancer prevention carcinogenesis metastasis prevention radiotherapy screening

Editors and affiliations

  • Waun Ki Hong
    • 1
  • Randal S. Weber
    • 1
  1. 1.M. D. Anderson Cancer CenterThe University of TexasHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-2023-8
  • Copyright Information Kluwer Academic Publishers 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5837-4
  • Online ISBN 978-1-4615-2023-8
  • Series Print ISSN 0927-3042
  • About this book