Recent Advances in Clinical Trial Design and Analysis

  • Peter F. Thall

Part of the Cancer Treatment and Research book series (CTAR, volume 75)

Table of contents

  1. Front Matter
    Pages i-x
  2. David L. DeMets, Gordon Lan
    Pages 1-27
  3. Dennis O. Dixon, Jeffrey M. Albert
    Pages 29-47
  4. Peter F. Thall, Richard M. Simon
    Pages 49-71
  5. D. Y. Lin
    Pages 73-93
  6. Michael LeBlanc, John Crowley
    Pages 113-124
  7. Richard M. Simon, Dennis O. Dixon, Boris Freidlin
    Pages 155-175
  8. Richard D. Gelber, Shari Gelber
    Pages 225-246
  9. Back Matter
    Pages 247-258

About this book


Clinical trials have two purposes -- to treat the patients in the trial, and to obtain information which increases our understanding of the disease and especially how patients respond to treatment. Statistical design provides a means to achieve both these aims, while statistical data analysis provides methods for extracting useful information from the trial data.
Recent advances in statistical computing have enabled statisticians to implement very rapidly a broad array of methods which previously were either impractical or impossible. Biostatisticians are now able to provide much greater support to medical researchers working in both clinical and laboratory settings. As our collective toolkit of techniques for analyzing data has grown, it has become increasingly difficult for biostatisticians to keep up with all the developments in our own field. Recent Advances in Clinical Trial Design and Analysis brings together biostatisticians doing cutting-edge research and explains some of the more recent developments in biostatistics to clinicians and scientists who work in clinical trials.


AIDS Anästhesie-Informations-Management-System data analysis diagnostics statistics

Editors and affiliations

  • Peter F. Thall
    • 1
  1. 1.Department of BiomathematicsThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5830-5
  • Online ISBN 978-1-4615-2009-2
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site