Neural Cell Specification

Molecular Mechanisms and Neurotherapeutic Implications

  • Bernhard H. J. Juurlink
  • Patrick H. Krone
  • William M. Kulyk
  • Valerie M. K. Verge
  • J. Ronald Doucette

Part of the Altschul Symposia Series book series (ALSS, volume 3)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Pattern Formation in the Vertebrate CNS

    1. Front Matter
      Pages 1-1
    2. M. Mark, F. M. Rijli, T. Lufkin, P. Dollé, P. Gorry, P. Chambon
      Pages 3-16
    3. Michèle Studer, Heather Marshall, Heike Pöpperl, Atsushi Kuroiwa, Robb Krumlauf
      Pages 17-28
    4. Patrick Tremblay, Susanne Dietrich, Anastasia Stoykova, Edward T. Stuart, Peter Gruss
      Pages 29-50
    5. Anthony-Samuel LaMantia, Melissa C. Colbert, Elwood Linney
      Pages 51-65
  3. Genetic Determinants of Neural Cell Fate

    1. Front Matter
      Pages 67-67
    2. Massimo Gulisano, Vania Broccoli, Fabio Spada, Edoardo Boncinelli
      Pages 69-84
    3. Bogi Andersen, Linda Erkman, Peng Li, Chijen R. Lin, Sheng-Cai Lin, Robert McEvilly et al.
      Pages 85-95
    4. Andrew P. Jarman, Yuh Nung Jan
      Pages 97-104
    5. S. L. Pfaff, T. Yamada, T. Edlund, T. M. Jessell
      Pages 111-124
  4. Neural Cell Differentiation

    1. Front Matter
      Pages 125-125
    2. S. J. Birren, J. M. Verdi, D. J. Anderson
      Pages 127-138
    3. C. P. Austin, C. L. Cepko
      Pages 139-143
    4. Diana Collazo, Ron McKay
      Pages 145-170
    5. Andrew K. Groves, Mark Noble
      Pages 171-184
    6. S. Weiss, S. Ahmed, A. Vescovi, B. A. Reynolds
      Pages 185-188
    7. J.-P. Julien, F. Côté, G. Charron, J.-F. Collard
      Pages 209-216
  5. Strategies for Neural Cell Replacement in Neurodegenerative Disorders

    1. Front Matter
      Pages 217-217
    2. J. R. Sladek Jr., J. D. Elsworth, R. H. Roth, B. C. Blanchard, J. R. Taylor, T. J. Collier et al.
      Pages 219-230
    3. Geoffrey Raisman
      Pages 241-247
    4. Douglas K. Anderson, Dena R. Howland, Paul J. Reier
      Pages 249-266
    5. P. Aebischer, S. A. Tan, N. A. Pochon, E. E. Baetge, A. C. Kato
      Pages 275-284
    6. Bernhard H. J. Juurlink, Patrick H. Krone, William M. Kulyk, Valerie M. K. Verge, J. Ronald Doucette
      Pages 290-290
  6. Back Matter
    Pages 291-310

About this book


The last decades have witnessed a radical change in our views on central nervous system damage and repair. This change is not only due to the emergence of new powerful tools for the analysis of the brain and its reactions to insults, but it also reflects a conceptual change in the way we approach these problems. As an illustration to this development, it is instructive to go back to the proceedings of a meeting at the NIH in 1955 edited by William F. Windle, which summarizes the disillusioned and pessimistic view on CNS regeneration prevailing at the time. While this generation of researchers were well aware of the issues at stake, they felt they had reached the end of the road; the approaches they had pursued had got stuck and the tools available could not take them any further. I can very well imagine that the participants, most of them leaders in the field, left that conference feeling they had heard their field being sentenced to death.


Embryo Enten Mammalia Nervous System development genes migration molecular mechanisms regulation

Editors and affiliations

  • Bernhard H. J. Juurlink
  • Patrick H. Krone
  • William M. Kulyk
  • Valerie M. K. Verge
  • J. Ronald Doucette
    • 1
  1. 1.University of SaskatchewanSaskatoonCanada

Bibliographic information