The Pineal Gland and Its Hormones

Fundamentals and Clinical Perspectives

  • Franco Fraschini
  • Russel J. Reiter
  • Bojidar Stankov

Part of the NATO ASI Series book series (NSSA, volume 277)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Pineal Gland Regulation

    1. Jörg H. Stehle, Nicholas S. Foulkes, Marjan Rikkers, Paul Pevet, Paolo Sassone-Corsi
      Pages 13-20
    2. Paul Pévet, Bruno Pitrosky, Mireille Masson-Pévet, Raymond Kirsch, Bernard Canguilhem, Berthe Vivien-Roels
      Pages 33-47
  3. Melatonin Receptors

    1. Bojidar Stankov, Franco Fraschini
      Pages 49-59
    2. Margarita L. Dubocovich, Diana N. Krause, Stanca Iacob, Susan Benloucif, Monica I. Masana
      Pages 61-74
    3. Mohan Viswanathan, Simona Capsoni, Juan M. Saavedra
      Pages 75-81
    4. Peter J. Morgan, Perry Barrett
      Pages 83-94
  4. Melatonin in the Circadian System

    1. Michael H. Hastings, Elizabeth S. Maywood, Francis J. P. Ebling
      Pages 95-105
    2. D. P. Cardinali, D. A. Golombek, R. E. Rosenstein, B. A. Kanterewicz, M. Fiszman
      Pages 119-130
  5. Melatonin Analogs

    1. Franco Fraschini, Bojidar Stankov
      Pages 131-138
    2. Philippe Delagrange, Pierre Renard, Daniel Henri Caignard, Béatrice Guardiola-Lemaître
      Pages 139-153
    3. Francesco Scaglione, Daniele Esposti, Marco Mariani, Germana Demartini, Valeria Lucini, Franco Fraschini
      Pages 155-164
  6. Melatonin in Humans

    1. Josephine Arendt
      Pages 165-171
    2. Alfred J. Lewy, Robert L. Sack, Saeeduddin Ahmed, Vance K. Bauer, Mary L. Blood
      Pages 173-182
    3. J. David Parkes
      Pages 183-197
    4. Lennart Wetterberg
      Pages 199-208
    5. William A. Robinson, Lyndah Dreiling, Rene Gonzalez, Carol Balmer
      Pages 219-225
  7. Back Matter
    Pages 227-233

About this book


This volume contains the written contributions to the proceedings of a workshop related to the pineal gland and its hormones, which was held in Erice, Italy, on June 7 -June 13, 1994. This series of workshops, which began in 1982 and which have been held at four-year intervals since that time, has provided important continuity for advancing the state of knowledge relating to this very important investigative area. The enthusiasm for these conferences has increased steadily, as reflected in the number of individuals applying to attend and in the input of individuals who participate in the meeting. The 1994 meeting was important because of its timeliness. In the two years preceding the meeting a number of revolutionary discoveries were made relative to the actions of the pineal hormone melatonin. The Xenopus melatonin receptor was cloned, melatonin was demonstrated to be a potent antioxidant, the significance of melatonin receptors at the level of pars tuberalis in the regulation of the hypothalamo-pituitary-gonadal axis was questioned, a number of melatonin receptor analogues were discovered and successfully utilized, the mechanisms by which melatonin retards initiation and promotion of cancer was further elucidated, the clinical aspects of the pineal gland was re-scrutinized. Reviews relating to each of these subjects, as well as many others, are contained in this proceedings book. This volume represents an up-to-date repository for the most recent information related to this rapidly advancing field.


cancer development evolution hormone neurotransmitter research

Editors and affiliations

  • Franco Fraschini
    • 1
  • Russel J. Reiter
    • 2
  • Bojidar Stankov
    • 1
  1. 1.University of MilanMilanItaly
  2. 2.University of TexasSan AntonioUSA

Bibliographic information