Ocular Toxicology

  • Ingo Weisse
  • Otto Hockwin
  • Keith Green
  • Ramesh C. Tripathi

Table of contents

  1. Front Matter
    Pages i-x
  2. Welcome and Opening of the Congress

    1. Ingo Weisse
      Pages 1-6
  3. Ocular Electrophysiology

    1. Andrew M. Geller, Catherine M. Osborne, Robert L. Peiffer
      Pages 7-25
    2. Walter H. Bee, Rainhart Korte, Friedhelm Vogel
      Pages 53-61
    3. Peter Walter, Christoph Lüke, Werner Sickel
      Pages 63-67
    4. Yohko Yamashita, Kiyofumi Mochizuki, Hiroyuki Sakai, Makoto Torisaki, Jhoji Tanabe
      Pages 85-91
    5. Olivier Loget, Gérard Saint-Macary
      Pages 99-108
  4. Ocular Pharmacokinetics

    1. Marco Fabrizio Saettone
      Pages 109-120
    2. G. S. Polunin, M. N. Ivanov, A. A. Fedorov, A. N. Ovchinnikov
      Pages 135-144
    3. Jeffrey Grove, Gilles Chastaing, Marie-Paule Quint, Annouk Rozier, Bernard Plazonnet
      Pages 153-159
    4. V. Montoya, M. A. Company, M. Palmero, A. Orts
      Pages 161-165
    5. Kenjiro Sawa, Mitsushi Hikida, Hiroyuki Mibu, Eiich Shirasawa, Kenji Takase, Hiroshi Suda
      Pages 167-179
    6. Kayo Uchiyama, Naoko Asano, Masafumi Ogata, Toshiro Tanahashi, Makoto Torisaki, Kiyofumi Mochizuki et al.
      Pages 181-190
  5. Lens/Cataract

  6. In Vitro Methods

    1. Hans-Peter Klöcking, Ulf Schlegelmilch, Renate Klöcking
      Pages 255-261
    2. Nobuo Takahashi, Teiichiroh Murayama, Minoru Miyakoshi, Takayuki Kurihara
      Pages 263-267
    3. W. Naib-Majani, W. Breipohl, U. Sterzinsky, M. Takeda
      Pages 269-276
  7. Regulatory Affairs

    1. Michael D. Stonard, Peter H. Berry, Sandra J. Kennedy, George J. Krinke, Derek A. Stringer, Ingo Weisse
      Pages 277-280
    2. Sandra J. Kennedy, Peter H. Berry, Georg J. Krinke, Michael D. Stonard, Derek A. Stringer, Ingo Weisse
      Pages 281-285
  8. Miscellaneous

    1. Klaus Krauser, Edith Schneider, Robert Hermann, Wolfgang Jahn
      Pages 287-295
    2. Willy Neumann, Andrea L. Schulte-Neumann
      Pages 303-315
    3. W. Breipohl, C. Reitz, M. H. J. Ahrend, F. H. Grus, J. Bours
      Pages 317-326
    4. J. P. Gillet, G. De Burlet, S. Molon-Noblot, L. D. Wise, G. Durand-Cavagna, P. Duprat
      Pages 335-342
    5. W. Breipohl, C. Penzkofer, W. Naib-Majani, M. Rauwolf, O. Leip, A. Augustin et al.
      Pages 343-349
    6. Konrad Kohler, Helmuth Lilienthal, Eberhart Zrenner
      Pages 369-374
  9. Back Matter
    Pages 375-378

About this book


On behalf of the editorial board and the organizing committee of the 4th congress of the International Society of Ocular Toxicology (I SOT), held in AnnecyNeyrier du Lac, France, October 9 -13, 1994, we are pleased to present to the ocular toxicology community this indexed volume of our congress proceedings. The 4th congress was designed primarily to facilitate and update the knowledge in ocular electrophysiology and ocular pharmacokinetics, in both the clinical and preclinical aspects. The outcome of this 4th congress, established in this volume, is a useful contribution to the meth­ odology in both fields and will hopefully assist in the evaluation and interpretation of ocular findings recorded in animal studies on drugs and other chemicals, in order to protect human health. Undoubtedly, work on the mechanisms of ocular toxicology in the process of pharmaceutical development must continue and these proceedings, embodying the presented papers, will add to the data base. The editors, the congress organizing committee and the members of the International Society of Ocular Toxicology thank the speakers who gave their time, knowledge, and expertise to assist us in this project. The following manuscripts contain the main substance of each of the platform presentations and, in some cases, much more. Moreover, our thanks go to all the participants coming from a range of background- regulatory, academic and industrial -for their attention and excellent contributions during the discussion.


development drug human health kinetics organophosphorus pharmacokinetics physiology research retina toxicity toxicology

Editors and affiliations

  • Ingo Weisse
    • 1
  • Otto Hockwin
    • 2
  • Keith Green
    • 3
  • Ramesh C. Tripathi
    • 4
  1. 1.Boehringer Ingelheim KGIngelheimGermany
  2. 2.University of BonnBonnGermany
  3. 3.Medical College of GeorgiaAugustaUSA
  4. 4.South Carolina Eye InstituteColumbiaUSA

Bibliographic information