Brain Injury

  • Robert S. B. Clark
  • Patrick Kochanek

Part of the Molecular and Cellular Biology of Critical Care Medicine book series (MCCM, volume 2)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Óscar L. Alves, Ross Bullock
    Pages 1-36
  3. Michael J. Bell, John M. Hallenbeck
    Pages 57-70
  4. Douglas S. DeWitt, Donald S. Prough
    Pages 71-97
  5. Maria Cristina Morganti-Kossmann, Mario Rancan, Philip F. Stahel, Viviane I. Otto, Thomas Kossmann
    Pages 99-114
  6. Yong Y. Han, Ian J. Reynolds
    Pages 145-161
  7. Larry Jenkins, C. Edward Dixon, Grant Peters, Wei-Min Gao, Xiaopeng Zhang, P. David Adelson et al.
    Pages 163-180
  8. Michael J. Whalen, Michael A. Moskowitz
    Pages 181-198
  9. Xiaopeng Zhang, Margaret A. Satchell, Robert S. B. Clark, Paula D. Nathaniel, Patrick M. Kochanek, Steven H. Graham
    Pages 199-230
  10. Jimmy W. Huh, Mark A. Helfaer, Tracy K. McIntosh, Kathryn E. Saatman
    Pages 249-265
  11. Anthony E. Kline, Larry W. Jenkins, Hong Q. Yan, C. Edward Dixon
    Pages 267-294
  12. Nabil J. Alkayed, Michael M. Wang, Patricia D. Hurn
    Pages 295-315
  13. Mary E. Kerr, Steven T. DeKosky, Andrew Kay, Donald W. Marion
    Pages 317-347
  14. David S. Warner
    Pages 349-367
  15. Back Matter
    Pages 369-384

About this book


Brain Injury is the second volume in the book series, Molecular and Cellular Biology of Critical Care Medicine. In this volume, a group of internationally regarded experts in important areas of neuroscience and neurointensive care research address the molecular and cellular basis of acute brain injury.
This text covers acute brain injury within a context relevant to the care of patients with critical neurologic injuries such as cardiac arrest, trauma and stroke. It includes recent data pertaining to established pathways such as neurotransmission, exitotoxicity, ionic-mechanisms, oxidative stress, inflammation, and cerebral vascular injury. In addition, rapidly developing areas such as cell signaling, adenosine pharmacology, apoptosis, mitochondrial dysfunction, neurocytoskeletal changes, and the role of trophic factors are reviewed from the level of in vitro modeling to human data. Other topics covered that are highly clinically relevant include the effect of genetic background and gender differences in outcome after brain injury, preconditioning, and the effects of currently used anesthetics and sedative agents in patients with brain injury.


Alzheimer Neurointensiv Trauma adenosine intensive care medicine neuroscience

Editors and affiliations

  • Robert S. B. Clark
    • 1
  • Patrick Kochanek
    • 2
  1. 1.Pediatric Critical Care MedicineChildren’s Hospital of PittsburghPittsburghUSA
  2. 2.Safar Center for Resuscitation ResearchPittsburghUSA

Bibliographic information