Cardiac Allograft Rejection

  • G William Dec
  • Jagat Narula
  • Manel Ballester
  • Ignasi Carrio

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Immunopathology of Cardiac Allograft Rejection

    1. Front Matter
      Pages 1-1
    2. Marlene L. Rose, Sudhir Kushwaha, Deirdre Cunningham
      Pages 21-47
    3. Petri Koskinen, Jussi Tikkanen, Roope Sihvola, Pekka Häyry, Karl Lemström
      Pages 49-64
    4. Jay Bruce Sundstrom, Kimberley Cecile Jollow, Aftab Ahmed Ansari
      Pages 65-88
    5. Mireia Puig, Navneet Narula, Jagat Narula
      Pages 89-100
    6. Elizabeth H. Hammond, Robert L. Yowell, Dale G. Renlund
      Pages 101-125
    7. Thomas Wekerle, Josef Kurtz, Megan Sykes
      Pages 127-151
    8. Kwabena Mawulawde, Joren C. Madsen
      Pages 153-173
  3. Clinical Assessment and Management of Cardiac Allograft Rejection

    1. Front Matter
      Pages 175-175
    2. Barbara Czerska, Mary E. Keohane, Edward F. Philbin
      Pages 177-196
    3. J. F. Gummert, T. Ikonen, R. E. Morris
      Pages 233-266
    4. Ilan S. Wittstein, Edward K. Kasper
      Pages 267-284
  4. Newer Diagnostic Tools for the Management of Cardiac Allograft Rejection

    1. Front Matter
      Pages 285-285
    2. Rohit Srivastava, Jeffrey D. Hosenpud
      Pages 287-297
    3. Nadia Giannetti, Hannah A. Valantine
      Pages 299-320
  5. Radionuclide Imaging for Surveillance of Cardiac Allograft Rejection

  6. Back Matter
    Pages 399-434

About this book


Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy.
This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.


Immunosuppression cardiac imaging cardiovascular heart heart transplantation transplantation

Editors and affiliations

  • G William Dec
    • 1
  • Jagat Narula
    • 2
  • Manel Ballester
    • 3
  • Ignasi Carrio
    • 4
  1. 1.Heart Failure & Transplantation ServiceHarvard Medical SchoolBostonUSA
  2. 2.Heart Failure/Transplantation CenterHahnemann University School of MedicinePhiladelphiaUSA
  3. 3.Department of Cardiology, Hospital Universitari Arnau de VilanovaUniversitat de LleidaLleidaSpain
  4. 4.Nuclear Medicine Department, Hospital de Sant PauAutonomous University of BarcelonaBarcelonaSpain

Bibliographic information