Genetics of Diabetes Mellitus

  • William L. LoweJr.

Part of the Endocrine Updates book series (ENDO, volume 10)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Steven H. Nye, Soumitra Ghosh
    Pages 1-23
  3. Alberto Pugliese
    Pages 25-42
  4. Pamela R. Fain, George S. Eisenbarth
    Pages 43-64
  5. Constantin Polychronakos, Alberto Pugliese
    Pages 65-77
  6. Philippe Froguel, Gilberto Velho
    Pages 79-89
  7. Sabine Hofmann, Matthias F. Bauer, Klaus-Dieter Gerbitz
    Pages 91-108
  8. Josep Vidal, Steven E. Kahn
    Pages 109-131
  9. Domenico Accili, Byung-Chul Park
    Pages 191-205
  10. William L. Lowe Jr.
    Pages 207-230
  11. Wen-Chi Hsueh, Braxton D. Mitchell, Alan R. Shuldiner
    Pages 231-250
  12. Back Matter
    Pages 251-255

About this book

Introduction

Genetics of Diabetes Mellitus is intended to be a resource for both researchers in the field as well as endocrinologists, diabetologists, and geneticists who seek to learn more about this rapidly changing and important field. The text contains chapters from experts in the area who review aspects of the genetics of both type 1 and 2 diabetes mellitus as well as various syndromic forms of diabetes. The chapters are approachable for those who are not experts in the field of genetics but also comprehensive, so as to serve as an important resource for researchers interested in the genetics of diabetes mellitus.
A description of basic concepts of the genetics of complex diseases like type 1 and type 2 diabetes is provided as background. Type 1 diabetes is addressed in chapters exploring genetic determinants that affect the autoimmune process characteristic of type 1 diabetes, the role of the insulin gene in the pathogenesis of type 1 diabetes and additional genes that may impact upon the risk of type 1 diabetes. The impact of genetic determinants on the pathophysiology of type 2 diabetes is covered, as are chapters that address specific genes that are important for the development of type 2 diabetes. Finally, syndromic forms of diabetes, including Maturity Onset Diabetes of the Young and mitochondrial diabetes, and the insight that these disorders provide into more common forms of diabetes are reviewed.
Thus, this comprehensive and up-to-date text will serve as an important resource for those actively engaged in research in this area and clinicians treating these patients to provide an up-to-date entrée for those seeking to become more knowledgeable in the area.

Keywords

Diabetes Diabetes mellitus genes genetics insulin insulin resistance

Editors and affiliations

  • William L. LoweJr.
    • 1
  1. 1.Northwestern University Medical SchoolChicagoUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-1597-5
  • Copyright Information Springer-Verlag US 2001
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5633-2
  • Online ISBN 978-1-4615-1597-5
  • Series Print ISSN 1566-0729
  • About this book