Mechanisms and Consequences of Proton Transport

  • Tetsuro Urushidani
  • John G. Forte
  • George Sachs

Table of contents

  1. Front Matter
    Pages iii-xiii
  2. Structure and Function of H,K-ATPase — Molecular Basis for Drug Targets

    1. Olga Vagin, Keith Munson, Jai Moo Shin, Nils Lambrecht, Steve Karlish, George Sachs
      Pages 1-17
    2. Gail Adams, Manoranjani Tillekeratne, Nikolay B. Pestov, Nikolai N. Modyanov
      Pages 19-31
    3. Gilles Crambert, Pascal Beguin, Udo Hasler, Kathi Geering
      Pages 33-41
    4. Thomas D. Dubose Jr., Juan Codina, Jian Li
      Pages 53-58
    5. Shinji Asano, Tohru Kimura, Takeguchi Noriaki
      Pages 59-70
    6. Jan Joep H. H. M. de Pont, Jan B. Koenderink, Herman G. P. Swarts, Peter H. G. M. Willems
      Pages 71-82
  3. Helicobacter Pylori and Mucosal Protection

    1. B. J. Appelmelk, M. P. Bergman, A. V. D. Aar, W. Lakhai, M. M. D’Elios, A. Azzurri et al.
      Pages 101-106
    2. Ban-Hock Toh, Mark Biondo, Aiden Marshall, Deanne Greenwood, John Sentry, Frank Alderuccio
      Pages 107-114
    3. Akiko Tanaka, Shoko Hase, Tohru Miyazawa, Kenji Kanatsu, Koji Takeuchi
      Pages 135-137
    4. Osamu Furukawa, Masahiko Hirokawa, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz
      Pages 139-142
    5. Masahiko Hirokawa, Osamu Furukawa, Paul H. Guth, Eli Engel, Shaoyou Chu, Marshall H. Montrose et al.
      Pages 143-145
  4. Gene Targeting Mouse — Mechanisms of Acid Secretion and Cell Proliferation

    1. Ian R. Van Driel, Teo V. Franic, Louise M. Judd, Simon P. Barrett, Katrina L. Scarff, Linda C. Samuelson et al.
      Pages 147-157
    2. G. J. Dockray, G. Bate, K. Hormi, T. Wang, A. Varro, R. Dimaline
      Pages 159-167
    3. Koji Takeuchi, Shinichi Kato, Yusaku Komoike, Yoshihiro Ogawa, Masanori Takeeda
      Pages 169-180
  5. Signal Transduction in the Parietal Cell — Pathway to Activation

    1. Andrea Todisco, Nonthalee Pausawasdi, Saravanan Ramamoorthy, John Del Valle, Rebecca W. Van Dyke, Frederick K. Askari
      Pages 197-207
    2. Ursula Seidler, Oliver Bachmann, Thorsten Sonnentag, Alexander Heinzmann, Wolf-Kristian Siegel, Andreas Mack et al.
      Pages 221-232
    3. Danuta H. Malinowska, Ann M. Sherry, Kirti P. Tewari, John Cuppoletti
      Pages 233-245
    4. F. Grahammer, Herling Aw, T. Von Hahn, D. Heitzmann, H. J. Lang, A. Schmitt-Gräff et al.
      Pages 247-254
    5. John Cuppoletti, Kirti P. Tewari, Ann M. Sherry, Danuta H. Malinowska
      Pages 255-264
    6. Fabián Michelangeli, José Francisco Pérez, Marie Christine Ruiz
      Pages 265-273
    7. Yumiko Mizukawa, Tomohiro Nishizawa, Taku Nagao, Ken Kitamura, Tetsuro Urushidani
      Pages 279-282
  6. Cytoskeleton and Membrane Trafficking — The Gastric Parietal Cell as a Model

  7. Back Matter
    Pages 365-372

About this book


This volume represents the proceedings of the 9th International Proton Transport Conference, "Mechanisms and Consequences of Proton Transport" held in Leura, Australia, August 19 -21, 200 I. This conference has been held since 1971 every 3 to 4 years with few exceptions in association with the Congress of the International Union of Physiological Sciences. The first meeting was held in Frankfurt, Germany, at the Max-Planck'Institute. Countries hosting the conference have been Germany (twice), Sweden (twice), India, Canada, USA, Great Britain, and now Australia. Over the past 30 years participants at these Proton Transport Conferences have been principal contributors to the major discoveries in the physiology, biochemistry and pharmacology of gastric acid secretion. These include development of the H2-receptor blockers, defining the signaling pathways for the regulation of acid secretion, identifying the gastric proton pump, discovery and development of proton pump inhibitory drugs, and elucidating the physiology and biochemistry of Helicobacter pylori.


ATP Activation Amino acid Calcium Colon gene expression influence proteins regulation

Editors and affiliations

  • Tetsuro Urushidani
    • 1
  • John G. Forte
    • 2
  • George Sachs
    • 3
  1. 1.Graduate School of Pharmaceutical ScienceThe University of TokyoJapan
  2. 2.Dept. of Molecular & Cell BiologyUniversity of California at BerkeleyUSA
  3. 3.Center for Ulcer Research & EducationUniversity of CaliforniaLos AngelesUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5330-0
  • Online ISBN 978-1-4615-0971-4
  • Buy this book on publisher's site