CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology

  • Jürgen Langner
  • Siegfried Ansorge

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Carmen Mrestani-Klaus, Susan Lorey, Jürgen Faust, Frank Bühling, Klaus Neubert
    Pages 1-24
  3. Uwe Lendeckel, Marco Arndt, Beate Firla, Carmen Wolke, Thomas Wex, Siegfried Ansorge
    Pages 25-49
  4. Marie-Claude Fournié-Zaluski, Bernard P. Roques
    Pages 51-94
  5. Shripad V. Bhagwat, Yasuhiro Okamoto, Linda H. Shapiro
    Pages 123-139
  6. Dagmar Riemann, Tanja Blosz, Jens Wulfänger, Jürgen Langner, Alexander Navarrete Santos
    Pages 141-170
  7. Catherine A. Abbott, Mark D. Gorrell
    Pages 171-195
  8. Thilo Kähne, Sabine Wrenger, Andre Manutscharow, Dirk Reinhold
    Pages 197-222
  9. Ingrid de Meester, Christine Durinx, Paul Proost, Simon Scharpé, Anne-Marie Lambier
    Pages 223-257
  10. Torsten Hoffmann, Hans-Ulrich Demuth
    Pages 259-278
  11. Stefan Brocke, Dirk Reinhold, Andreas Steinbrecher
    Pages 279-287
  12. Martin Hildebrandt, Hans-Ulrich Demuth, Werner Reutter
    Pages 289-300
  13. Back Matter
    Pages 301-310

About this book


The idea to compile recent results on the ectoenzymes aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 arose from the great interest given by readers world-wide to the two proceedings volumes edited by us in 1997 and 2000 (Ansorge and Langner, 1997; Langner and Ansorge, 2000). These volumes contained the presentations at two symposia held in Magdeburg (Germany) in 1996 and 1999 under the title "Cellular peptidases in immune functions and diseases", which was also the name of the Sonderforschungsbereich in Magdeburg, sponsored by the Deutsche Forschungsgemeinschaft between 1995 and 2001. Our groups in Magdeburg and Halle during the last two decades have provided results on these two enzymes in cells of the hematopoietic system that justify a review in an edited monograph like the present one (see the reviews by Kahne et at. , 1999; Lendeckel et at. ,1999; Riemann et at. , 1999). There are, however, many other groups in Europe, US and Japan which made important contributions to this field and particularly in topics improving the understanding of physiological and pathophysiological roles ofAPN/CD13 and DPIV/CD26. Therefore we decided to invite some of them to contribute reviews of their results to this book. Having worked for about 40 years in the field of proteolysis, for both of us to see the development of activities and knowledge from protein chemistry and enzymology to physiology and pathophysiology and even to therapy is very stimulating and fascinating. Of course, this development also reflects the dramatic improvement and refinement of methods.


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Editors and affiliations

  • Jürgen Langner
    • 1
  • Siegfried Ansorge
    • 2
  1. 1.Martin Luther UniversityHalle-WittenbergGermany
  2. 2.Otto von Guericke UniversityMagdeburgGermany

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic / Plenum Publishers, New York 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5161-0
  • Online ISBN 978-1-4615-0619-5
  • Buy this book on publisher's site