© 2002

Cyclic ADP-Ribose and NAADP

Structures, Metabolism and Functions

  • Hon Cheung Lee

Table of contents

  1. Thomas A. White, Deepak A. Deshpande, Soner Dogan, Reynold A. Panettieri, Timothy F. Walseth, Mathur S. Kannan
    Pages 427-449
  2. Back Matter
    Pages 451-460

About this book


In the past decade we have witnessed the birth and maturing of a field of research centering on the Ca2+ signaling functions of cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP), which structures and mechanisms of action are truly unique among all Ca2+ messengers. A wide range of physiological functions are now known to be mediated by them in cells spanning three biological kingdoms from protist, plant to animal. This is the first book devoted entirely to the field. The story behind the emergence of the field is told and followed by comprehensive reviews of the enzymology, regulations and gene structures of ADP-ribosyl cyclases responsible for metabolizing cADPR and NAADP. Also covered is some of the current methodology developed for and widely used in the field. The rest of the book focuses on and details the Ca2+ signaling mechanisms and specific physiological functions of these two messengers in various cellular systems.


Calcium Nucleotide metabolism pharmacology research synthesis

Editors and affiliations

  • Hon Cheung Lee
    • 1
  1. 1.MinneapolisUSA

Bibliographic information

  • Book Title Cyclic ADP-Ribose and NAADP
  • Book Subtitle Structures, Metabolism and Functions
  • Authors Hon Cheung Lee
  • DOI
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-1-4020-7281-9
  • Softcover ISBN 978-1-4613-4996-9
  • eBook ISBN 978-1-4615-0269-2
  • Edition Number 1
  • Number of Pages XVIII, 460
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pharmacology/Toxicology
    Biochemistry, general
  • Buy this book on publisher's site