Molecular and Cellular Biology of Neuroprotection in the CNS

  • Christian Alzheimer

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 513)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Neuronal Cell Death Overview of Basic Mechanisms

    1. Front Matter
      Pages 1-1
    2. Thomas Gillessen, Samantha L. Budd, Stuart A. Lipton
      Pages 3-40
    3. Richard S. Morrison, Yoshito Kinoshita, Mark D. Johnson, Saadi Ghatan, Joseph T. Ho, Gwenn Garden
      Pages 41-86
    4. Ann Logan, Martin Berry
      Pages 115-158
  3. Ion Channels, Receptors and Signaling Pathways

    1. Front Matter
      Pages 159-159
    2. Rod J. Sayer
      Pages 183-196
    3. Peter J. Flor, Giuseppe Battaglia, Ferdinando Nicoletti, Fabrizio Gasparini, Valeria Bruno
      Pages 197-223
    4. Trevor W. Stone
      Pages 249-280
    5. Midori A. Yenari
      Pages 281-299
  4. Neurotrophic Factors as Neuroprotective Agents

    1. Front Matter
      Pages 301-301
    2. Georg Dechant, Harald Neumann
      Pages 303-334
    3. Christian Alzheimer, Sabine Werner
      Pages 335-351
    4. Klaus Unsicker, Kerstin Krieglstein
      Pages 353-374
    5. Hugo H. Marti
      Pages 375-394
  5. Advances in Drug Delivery to CNS Neurons

    1. Front Matter
      Pages 395-395
    2. Ulrike Blömer, Arnold Ganser, Michaela Scherr
      Pages 431-451
  6. Neuroprotective Strategies in Animal and in Vitro Models of Neuronal Damage

    1. Front Matter
      Pages 453-453
    2. Matthias Endres, Ulrich Dirnagl
      Pages 455-473
  7. Back Matter
    Pages 497-501

About this book


Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases. This book brings together leading experts from neurobiology, neurophysiology, neuropharmacology, neuroimmunology and clinical neuroscience to highlight the most recent milestones in this rapidly evolving field. The book will serve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies.


Nervous System Neuroscience neurons neurophysiology neurotoxicity physiology regulation

Editors and affiliations

  • Christian Alzheimer
    • 1
  1. 1.Institute of PhysiologyUniversity of KielKielGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4934-1
  • Online ISBN 978-1-4615-0123-7
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site