Studies on Periodontal Disease

  • Daisuke Ekuni
  • Maurizio Battino
  • Takaaki Tomofuji
  • Edward E. Putnins

Table of contents

  1. Front Matter
    Pages i-xii
  2. Oxidative Stress in Periodontal Diseases (Basic Science)

  3. Oxidative Stress in Periodontal Diseases (Clinical Studies)

    1. Front Matter
      Pages 131-131
    2. Luigi Nibali, Brian Henderson, Giovanni Li Volti, Nikos Donos
      Pages 133-146
    3. Takaaki Tomofuji, Daisuke Ekuni, Manabu Morita
      Pages 147-156
    4. Noriko Ebe, Miki Hara-Yokoyama, Yuichi Izumi
      Pages 157-164
  4. Periodontal Diseases and Systemic Diseases (Possible Link to Other Organs)

    1. Front Matter
      Pages 165-165
    2. Daisuke Ekuni, Takaaki Tomofuji, Manabu Morita
      Pages 183-195
    3. Koichiro Irie, Daisuke Ekuni, Takaaki Tomofuji, Manabu Morita
      Pages 197-209
    4. Tomoko Komatsu, Masaichi-Chang-Il Lee
      Pages 211-223
  5. Future Strategies (Control of ROS, Roles of Nutrition/Antioxidants and Application to Dentistry)

    1. Front Matter
      Pages 225-225
    2. José L. Quiles, Alfonso Varela-López
      Pages 251-278
    3. Takaaki Tomofuji, Daisuke Ekuni, Shinsuke Mizutani, Manabu Morita
      Pages 279-305
  6. Daisuke Ekuni, Maurizio Battino, Takaaki Tomofuji, Edward E. Putnins
    Pages E1-E1
  7. Back Matter
    Pages 345-370

About this book


The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease.

This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.


Chronic inflammatory diseases HMGB1 Monoamine oxidase Periodontitis

Editors and affiliations

  • Daisuke Ekuni
    • 1
  • Maurizio Battino
    • 2
  • Takaaki Tomofuji
    • 3
  • Edward E. Putnins
    • 4
  1. 1.Department of Preventive DentistryOkayama University Graduate School of Medicine and Pharmaceutical SciencesOkayamaJapan
  2. 2.Dept of Science and Clinical Specialty Odontostomatology & BiochemistryPolytechnical University of Marche Faculty of MedicineAnconaItaly
  3. 3.Department of Preventive DentistryOkayama Univ Graduate School of Medicine Dentistry and Pharmaceutical SciencesOkayamaJapan
  4. 4.Dept of Oral Biological & Medical Scienc Laboratory of Periodontal BiologyUniversity of British Columbia Faculty of DentistryVancouverCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2014
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4614-9556-7
  • Online ISBN 978-1-4614-9557-4
  • Series Print ISSN 2197-7224
  • Series Online ISSN 2197-7232
  • Buy this book on publisher's site