Vascular Mechanisms in CNS Trauma

  • Eng H. Lo
  • Josephine Lok
  • MingMing Ning
  • Michael J. Whalen

Part of the Springer Series in Translational Stroke Research book series (SSTSR, volume 5)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Molecular Mechanisms

    1. Front Matter
      Pages 1-1
    2. Adam Chodobski, Brian J. Zink, Joanna Szmydynger-Chodobska
      Pages 3-28
    3. Philip H. Iffland II, Gerald A. Grant, Damir Janigro
      Pages 29-45
    4. David A. Hovda, Thomas C. Glenn
      Pages 47-54
    5. Arjun Khanna, Brian P. Walcott, Kristopher T. Kahle, Volodymyr Gerzanich, J. Marc Simard
      Pages 55-73
    6. Josephine Lok, Ken Arai, Shu-zhen Guo, Wendy Leung, Takakuni Maki, Deepti Navaratna et al.
      Pages 75-103
    7. Monisha A. Kumar, Douglas H. Smith, Sherman C. Stein
      Pages 105-124
    8. F. Anthony Willyerd, Philip E. Empey, Patrick M. Kochanek, Robert S. B. Clark
      Pages 125-140
    9. Yanlu Zhang, Ye Xiong, Asim Mahmood, Zheng Gang Zhang, Michael Chopp
      Pages 141-156
    10. Kunjan R. Dave, John W. Thompson, Jake T. Neumann, Miguel A. Perez-Pinzon, Hung W. Lin
      Pages 179-200
    11. Mibel M. Pabón, Travis Dailey, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Sandra Acosta et al.
      Pages 201-222
    12. W. Dalton Dietrich, Helen M. Bramlett
      Pages 223-235
  3. Experimental Models and Methods

    1. Front Matter
      Pages 237-237
    2. Xiaoshu Wang, Zhanyang Yu, Zhengbu Liao, Qi Liu, MingMing Ning, Xiaochuan Sun et al.
      Pages 239-253
    3. Sheng Chen, Damon Klebe, Alexander Vakhmyanin, Mutsumi Fujii, John H. Zhang
      Pages 255-267
    4. William M. Armstead, Monica S. Vavilala
      Pages 269-284
    5. Alpa Trivedi, Sang Mi Lee, Haoqian Zhang, Linda J. Noble-Haeusslein
      Pages 285-302
    6. Olena Glushakova, Stefania Mondello, Ronald L. Hayes
      Pages 303-331
    7. Teck Chuan Lim, Myron Spector
      Pages 333-352
    8. Eugene V. Golanov
      Pages 353-359
  4. Clinical Challenges and Opportunities

    1. Front Matter
      Pages 361-361
    2. Brian M. Cummings, Phoebe H. Yager, Sarah A. Murphy, Brian Kalish, Chetan Bhupali, Rebecca Bell et al.
      Pages 363-378
    3. Takeshi Maeda, Tatsuro Kawamata, Atsuo Yoshino, Yoichi Katayama
      Pages 379-389
    4. Jose Alberto Toranzo, Claudia S. Robertson
      Pages 391-400
    5. Philip M. Lewis, Marek Czosnyka, Piotr Smielewski, John D. Pickard
      Pages 401-420
    6. Steven L. Shein, Nikki Miller Ferguson, Michael J. Bell
      Pages 421-431
    7. Jennifer C. Munoz Pareja, Josephine Lok, Natan Noviski, Ann-Christine Duhaime
      Pages 433-444
    8. Da Zhi Liu, Glen C. Jickling, Boryana Stamova, Xinhua Zhan, Bradley P. Ander, Frank R. Sharp
      Pages 445-457
    9. Sherry H.-Y. Chou, Eng H. Lo, MingMing Ning
      Pages 459-471
  5. Back Matter
    Pages 505-518

About this book


Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.  Twenty nine chapters are arranged in three sections—Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities.  The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.


blood-brain barrier cerebral blood flow edema neuroprotection spinal cord injury traumatic brain injury

Editors and affiliations

  • Eng H. Lo
    • 1
  • Josephine Lok
    • 2
  • MingMing Ning
    • 3
  • Michael J. Whalen
    • 4
  1. 1.Departments of Neurology and RadiologyMassachusetts General Hospital Harvard Medical SchoolBostonUSA
  2. 2.Department of PediatricsMassachusetts General Hospital Harvard Medical SchoolBostonUSA
  3. 3.Department of NeurologyMassachusetts General Hospital Harvard Medical SchoolBostonUSA
  4. 4.Department of PediatricsMassachusetts General Hospital Harbard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2014
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine
  • Print ISBN 978-1-4614-8689-3
  • Online ISBN 978-1-4614-8690-9
  • Buy this book on publisher's site