Multiple Sclerosis Immunology

A Foundation for Current and Future Treatments

  • Takashi Yamamura
  • Bruno Gran

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Barbara B. Gawlik, David A. Hafler
    Pages 27-47
  3. Amy E. Lovett-Racke, Michael K. Racke
    Pages 49-70
  4. Nathalie Koning, Juan M. Ilarregui, Juan J. García-Vallejo, Yvette van Kooyk
    Pages 71-94
  5. Bernhard Hemmer, Markus C. Kowarik, Martin S. Weber
    Pages 95-114
  6. Mohamed El-Behi, Bogoljub Ciric, Abdolmohamad Rostami
    Pages 127-147
  7. Julia Y. Mescheriakova, Karim L. Kreft, Rogier Q. Hintzen
    Pages 197-228
  8. Pablo Villoslada, Lawrence Steinman
    Pages 257-268
  9. Bert A. ’t Hart, S. Anwar Jagessar, Krista Haanstra, Yolanda S. Kap, Jon D. Laman
    Pages 295-314
  10. Ali Manouchehrinia, Laura J. Edwards, Cris S. Constantinescu
    Pages 341-356
  11. Aiden Haghikia, Ralf Gold
    Pages 357-384
  12. Alasdair Coles, Joanne Jones
    Pages 385-399
  13. Sofia Abrahamsson, Miriam Mattoscio, Paolo A. Muraro
    Pages 401-431
  14. Laura Lovato, Nicole Kerlero de Rosbo, Antonio Uccelli
    Pages 433-455
  15. Back Matter
    Pages 457-461

About this book


The availability of powerful genome-wide association study technology, during the last five years, has shown that most of the “new” MS susceptibility loci are immune-response genes. It is clear that there is much novelty in the field of MS immunology, which has served as an impetus to invest in new therapies. Notably, most if not all of these are immunotherapies. Even the equally exciting field of cell-based therapies and neuro-regeneration may well rely on cells or growth factors that are no less immunomodulators than restorative of myelin and neural cell function.  Multiple Sclerosis Immunology  looks at MS immunology as the basis for the present and—even more—the future of treatments for this complex autoimmune condition. Both editors are immunologists, as well as clinical neurologists, and appreciate the importance of a sustained dialogue between basic and clinical scientists to ensure that “translation” is real and not just virtual.


Autoimmune Disease Demyelination Immunotherapy Multiple Sclerosis

Editors and affiliations

  • Takashi Yamamura
    • 1
  • Bruno Gran
    • 2
  1. 1.National Institute of NeuroscienceNational Center of Neurology and PsychiaTokyoJapan
  2. 2.Clinical NeurologyUniversity of NottinghamNottinghamUnited Kingdom

Bibliographic information