Protein Tyrosine Phosphatase Control of Metabolism

  • Kendra K. Bence

Table of contents

  1. Front Matter
    Pages i-xi
  2. Yang Xu, Benjamin G. Neel
    Pages 1-26
  3. Kendra K. Bence, Tony Tiganis
    Pages 71-89
  4. Mirela Delibegovic, Nimesh Mody
    Pages 91-105
  5. Águeda González-Rodríguez, Ángela M. Valverde
    Pages 107-127
  6. Pimonrat Ketsawatsomkron, David W. Stepp, Eric J. Belin de Chantemèle
    Pages 129-145
  7. Maria I. Kontaridis, Eleni V. Geladari, Charalampia V. Geladari
    Pages 147-167
  8. Zhao He, Sharon S. Zhang, Jianxiu Yu, Gen-Sheng Feng
    Pages 169-186
  9. Stephanie M. Stanford, Massimo Bottini, Nunzio Bottini
    Pages 203-220
  10. Ahmed Lawan, Anton M. Bennett
    Pages 221-238
  11. Peter J. Roach, Anna A. DePaoli-Roach
    Pages 239-262
  12. Back Matter
    Pages 263-273

About this book

Introduction

Tyrosine phosphorylation is a rapid and reversible protein modification catalyzed by the yin and yang activities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs).  A multitude of PTPs have been implicated in human disease, with a growing number of PTPs now known to play major roles in prevalent metabolic diseases including obesity and type 2 diabetes.  Recent studies into PTP function in the context of metabolism highlight the importance of understanding the specific substrates and binding partners of these enzymes, the regulation of PTP activity, and the cell/tissue specificity of PTP functions.  This volume contains chapters which highlight many aspects of PTP function in the context of metabolism.

Editors and affiliations

  • Kendra K. Bence
    • 1
  1. 1.Department of Animal BiologyUniversity of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-7855-3
  • Copyright Information Springer Science+Business Media New York 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4614-7854-6
  • Online ISBN 978-1-4614-7855-3
  • About this book