© 2013

Human Interphase Chromosomes

Biomedical Aspects

  • Yuri B. Yurov
  • Svetlana G. Vorsanova
  • Ivan Y. Iourov

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Y. Iourov
    Pages 1-8
  3. Gemma Bourne, Catherine Moir, Ural Bikkul, Mai Hassan Ahmed, Ian R. Kill, Christopher H. Eskiw et al.
    Pages 9-33
  4. Gustavo A. Folle, María Vittoria Di Tomaso, Laura Lafon-Hughes, Pablo Liddle
    Pages 35-51
  5. Ivan Y. Iourov, Svetlana G. Vorsanova, Yuri B. Yurov
    Pages 53-83
  6. Darren K. Griffin, Gothami Fonseka, Helen G. Tempest, Alan R. Thornhill, Dimitris Ioannou
    Pages 123-138
  7. Olga S. Mudrak, Liudmila V. Solovjeva, Vadim O. Chagin
    Pages 139-159
  8. Ivan Y. Iourov, Thomas Liehr, Svetlana G. Vorsanova, Yuri B. Yurov
    Pages 161-169
  9. Thomas Liehr, Hasmik Mkrtchyan, Marina Manvelyan, Tatyana Karamysheva, Elisabeth Klein, Samarth Bhatt
    Pages 171-178
  10. Svetlana G. Vorsanova, Yuri B. Yurov, Ivan Y. Iourov
    Pages 179-203
  11. Back Matter
    Pages 205-216

About this book


The beginning of interphase cytogenetics can be attributed to significant advances in human molecular genetics and cytogenetics. Owing to experimental and theoretical research at the interface between cellular and molecular levels of chromosomal organization and function, high-resolution techniques for chromosomal analysis (molecular cytogenetic techniques) have become available. Molecular cytogenetics is a branch of biomedical sciences that explores chromosomes at molecular and single-cell resolutions at all stages of the cell cycle. It also comprises the techniques that operate with either the entire genome or specific DNA sequences to analyze genomic structural and functional variations at chromosomal level. In postgenomic era, molecular cytogenetics has appreciably transformed and has given rise to a new field of genomics, called cytogenomics. As a result, new opportunities have emerged for analysis of human interphase chromosomes in almost all cell types and states at unprecedented resolution. In Human Interphase Chromosomes, the editors have provided an overview of current developments in the study of human interphase chromosomes with a special attention to available molecular cytogenetictechnologies for basic and clinical chromosome research.


chromosome cytogenetics developmental biology genetics

Editors and affiliations

  • Yuri B. Yurov
    • 1
  • Svetlana G. Vorsanova
    • 2
  • Ivan Y. Iourov
    • 3
  1. 1.Mental Health Research Center, Laboratory of CytogeneticsRussian Academy of Medical SciencesMoscowRussia
  2. 2.Institute of Pediatry & Children Surgery, Laboratory of Molecular Cytogenetics ofMinistry of HealthMoscowRussia
  3. 3.Mental Health Research Center, Laboratory of Molecular Brain GeneticsRussian Academy of Medical SciencesMoscowRussia

About the editors

^400 publications.


Svetlana G. Vorsanova (PhD, Dr. Sci, professor) is a head of laboratory of molecular cy^600 publications.


Yuri B. Yurov (PhD, Dr. Sci, professor; 1951-2017) was a pioneer of interphase molecular cytogenetics. He was the founding editor of Molecular Cytogenetics (BMC/Springer/Nature). He has (co-)authored >650 publications, including descriptions of groundbreaking studies in molecular cytogenetics of the human brain.

Bibliographic information