Book 2013

Pharmacoresistance in Epilepsy

From Genes and Molecules to Promising Therapies

Editors:

ISBN: 978-1-4614-6463-1 (Print) 978-1-4614-6464-8 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xii

  2. No Access

    Chapter

    Pages 1-9

    Pharmacoresistance and Epilepsy

  3. No Access

    Chapter

    Pages 11-25

    Genes Involved in Pharmacoresistant Epilepsy

  4. No Access

    Chapter

    Pages 27-46

    Pathological Oscillations in the Pharmacoresistant Epileptic Brain

  5. No Access

    Chapter

    Pages 47-57

    Molecular Mechanisms of Pharmacoresistant Epilepsy

  6. No Access

    Chapter

    Pages 59-76

    Modifications in the Seizures Susceptibility by Excitotoxic Neuronal Damage and Its Possible Relationship with the Pharmacoresistance

  7. No Access

    Chapter

    Pages 77-97

    Intracellular Pathways Associated with Neuronal Survival and Death in Epilepsy

  8. No Access

    Chapter

    Pages 99-113

    The Role of JNK Pathway in the Process of Excitotoxicity Induced by Epilepsy and Neurodegeneration

  9. No Access

    Chapter

    Pages 115-126

    Proteomics-Based Strategy to Identify Biomarkers and Pharmacological Targets in Temporal Lobe Epilepsy

  10. No Access

    Chapter

    Pages 127-147

    Abnormalities of GABA System and Human Pharmacoresistant Epilepsy

  11. No Access

    Chapter

    Pages 149-168

    Pharmacoresistant Epilepsy and Immune System

  12. No Access

    Chapter

    Pages 169-184

    Contribution of the Antiepileptic Drug Administration Regime in the Development and/or Establishment of Pharmacoresistant Epilepsy

  13. No Access

    Chapter

    Pages 185-197

    Experimental Models to Study Pharmacoresistance in Epilepsy

  14. No Access

    Chapter

    Pages 199-205

    Resistance to Epileptogenesis in the Neotropical Rodent Proechimys

  15. No Access

    Chapter

    Pages 207-224

    On the Development of New Antiepileptic Drugs for the Treatment of Pharmacoresistant Epilepsy: Different Approaches to Different Hypothesis

  16. No Access

    Chapter

    Pages 225-232

    Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy

  17. No Access

    Chapter

    Pages 233-252

    Vagus Nerve Stimulation for Intractable Seizures

  18. No Access

    Chapter

    Pages 253-263

    The Role of Neuromodulation in the Treatment of Refractory Epilepsy

  19. No Access

    Chapter

    Pages 265-289

    Transcranial Magnetic Stimulation and Refractory Partial Epilepsy

  20. No Access

    Chapter

    Pages 291-306

    Effects of Transcranial Focal Electrical Stimulation via Concentric Ring Electrodes on Seizure Activity

  21. No Access

    Chapter

    Pages 307-320

    Physical Exercise as a Strategy to Reduce Seizure Susceptibility

  22. Back Matter

    Pages 321-329