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Mucosal Immunology of Acute Bacterial Pneumonia

  • Alice Prince

Table of contents

  1. Front Matter
    Pages i-x
  2. David H. Dockrell, Paul J. Collini, Helen M. Marriott
    Pages 1-48
  3. Bart N. Lambrecht, Katrijn Neyt, Corine H. GeurtsvanKessel, Hamida Hammad
    Pages 49-66
  4. Jay K. Kolls
    Pages 67-82
  5. John C. Gomez, Qin Wang, Claire M. Doerschuk
    Pages 83-124
  6. Shawn J. Skerrett
    Pages 125-138
  7. Lee J. Quinton, Joseph P. Mizgerd
    Pages 159-183
  8. Megan N. Ballinger, Theodore J. Standiford
    Pages 185-212
  9. Jessica Humann, Kim LeMessurier, Elaine Tuomanen
    Pages 213-238
  10. Back Matter
    Pages 271-277

About this book

Introduction

In contrast to the substantial literature that focuses upon innate immune signaling in the gut, there is remarkably less known about the response of the airway to bacterial pathogens.  The purpose of this book will be to review the current status of theunderstanding of the pathogenesis of acute bacterial pneumonia, slanted toward the mucosal immunology of these infections.  It will describe, in general, the signaling cascades that control the proinflammatory response to bacterial infection in the lung. How innate immune signaling is orchestrated in response to specific common airway pathogens is addressed, targeting Staphylococus aureus (including MRSA), Streptococcus pneumoniae and Klebsiella pneumoniae.   By describing the general immunological responses to conserved bacterial components and then detailing how specific organisms cause infection, this book provides a targeted but comprehensive review of this important topic.

Keywords

Airway Pathogens Bacterial Pneumonia Gram-Negative Opportunists Mucosal Immunology

Editors and affiliations

  • Alice Prince
    • 1
  1. 1.Columbia UniversityNew YorkUSA

Bibliographic information