Table of contents

  1. Front Matter
    Pages i-x
  2. Myeloma Immune and Antibody Targets

    1. Front Matter
      Pages 1-1
    2. Ross Brown, P. Joy Ho, John Gibson, Douglas Joshua
      Pages 3-24
    3. Surinder S. Sahota, Natalia Savelyeva, Debora Joseph-Pietras, Niklas Zojer, Jason Rice
      Pages 73-110
    4. Roberto Bellucci, Edwin P. Alyea
      Pages 111-129
    5. Jooeun Bae, R. H. Prabhala, Nikhil C. Munshi
      Pages 131-154
  3. New Agents

    1. Front Matter
      Pages 155-155
    2. Robert Z. Orlowski
      Pages 157-180
    3. Abhishek Singla, Shaji Kumar
      Pages 181-213
    4. Anuj Mahindra, Jacob Laubach, Constantine Mitsiades, Paul Richardson
      Pages 215-228
    5. Alessandra Larocca, Antonio Palumbo
      Pages 229-255
  4. Back Matter
    Pages 277-287

About this book

Introduction

Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients.

 

This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.

Keywords

cancer cell signalling myeloma therapeutic targets

Editors and affiliations

  • Nikhil C. Munshi
    • 1
  • Kenneth C. Anderson
    • 2
  1. 1.Dana-Farber Cancer InstituteHarvard Medical SchoolBostonUSA
  2. 2.Dana-Farber Cancer Institute, Dept. Medical OncologyHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-5260-7
  • Copyright Information Springer Science+Business Media New York 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4614-5259-1
  • Online ISBN 978-1-4614-5260-7
  • About this book