Coronary Vasculature

Development, Structure-Function, and Adaptations

  • Robert J. Tomanek

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Robert J. Tomanek
    Pages 25-46
  3. Robert J. Tomanek
    Pages 47-57
  4. Robert J. Tomanek
    Pages 59-81
  5. Robert J. Tomanek
    Pages 83-100
  6. Robert J. Tomanek
    Pages 101-121
  7. Robert J. Tomanek
    Pages 123-141
  8. Robert J. Tomanek
    Pages 143-165
  9. Robert J. Tomanek
    Pages 167-188
  10. Robert J. Tomanek
    Pages 189-220
  11. Robert J. Tomanek
    Pages 221-246
  12. Robert J. Tomanek
    Pages 247-266
  13. Back Matter
    Pages 267-276

About this book


Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, and this volume covers the hierarchy of the coronary vasculature from its embryonic origins through its postnatal growth, adulthood, and senescence. Chapters address normal coronary development, coronary anomalies and their possible underlying developmental errors, coronary vessel adaptations to exercise training, aging, hypoxia, myocardial ischemia, and cardiac hypertrophy.

This comprehensive overview of current research in coronary vessels and myocardial perfusion was written by Dr. Robert J. Tomanek, Emeritus Professor of Anatomy and Cell Biology at the University of Iowa. The book reviews, discusses, and integrates findings from various areas of coronary vasculature research, and as a result, will be a valuable reference source for cardiovascular scientists and physicians for many years to come.


angiogenesis arteriogenesis epicardium infarction myocardial ischemia proepicardium tubulogenesis vasculogenesis

Authors and affiliations

  • Robert J. Tomanek
    • 1
  1. 1.Carver College of Medicine, Cardiovascular CenterUniversity of IowaIowa CityUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2013
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-1-4614-4886-0
  • Online ISBN 978-1-4614-4887-7
  • Buy this book on publisher's site