Cancer Immunotherapy

Paradigms, Practice and Promise

  • Tyler J. Curiel

Table of contents

  1. Front Matter
    Pages i-ix
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Cailin Moira Wilke, Shuang Wei, Lin Wang, Ilona Kryczek, Jingyuan Fang, Guobin Wang et al.
      Pages 17-44
  3. Passive Strategies to Boost Antitumor Immunity

    1. Front Matter
      Pages 45-45
    2. Donald R. Shaffer, Conrad Russell Y. Cruz, Cliona M. Rooney
      Pages 47-70
    3. K. F. Bol, G. Schreibelt, E. H. J. G. Aarntzen, I. J. M. de Vries, C. G. Figdor
      Pages 71-108
  4. Active Strategies to Boost Antitumor Immunity

    1. Front Matter
      Pages 109-109
    2. Marion Braun, Rachel Perret, Godehard Scholz, Pedro Romero
      Pages 111-146
    3. Dinja Oosterhoff, David T. Curiel, Tanja D. de Gruijl
      Pages 147-171
    4. Kim Margolin, Mark Lazarus, Howard L. Kaufman
      Pages 173-210
    5. Margaret K. Callahan, Jedd D. Wolchok, James P. Allison, Padmanee Sharma
      Pages 211-280
    6. Devalingam Mahalingam, Tyler J. Curiel
      Pages 335-376
    7. Devalingam Mahalingam, Michael J. Brumlik, Reinhard Waehler, David T. Curiel, Tyler J. Curiel
      Pages 377-396
  5. Additional Strategies and Considerations

  6. Back Matter
    Pages 475-483

About this book


This volume is a comprehensive discussion of the major factors affecting tumor immunology and a discussion of all major anti-cancer immunotherapeutic agents approved by the Food and Drug Administration of the United States and by European agencies. Many promising but unapproved agents in clinical trials are also discussed, as are key pre-clinical developments. The major challenges and intellectual issues facing investigators developing novel immunotherapeutics are discussed in detail as are conceptual developments influencing current and future treatment strategies.

Each chapter begins by defining all relevant key terms and concepts and provides pertinent background information so that the text will be accessible to newcomers to the field as well as to the expert. This text book should provide an excellent reference resource for investigators in tumor immunology, life sciences students, drug developers designing novel anti-cancer immunotherapeutics, and to other individuals with some scientific training wishing to gain a better understanding of the field of tumor immunotherapy.

Although the field is evolving rapidly, we have taken pains to ensure that information was as up to date as possible as the text went to press.


Anti-tumor immunity Cancer Cell Biology Immunotherapy Tumor

Editors and affiliations

  • Tyler J. Curiel
    • 1
  1. 1.San Antonio Cancer CenterSan AntonioUSA

Bibliographic information