Sleep Loss and Obesity

Intersecting Epidemics

  • Priyattam Shiromani
  • Tamas Horvath
  • Susan Redline
  • Eve Van Cauter

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Thomas Curie, Paul Franken
    Pages 1-12
  3. Hee-Kyung Hong, Wenyu Huang, Kathryn Moynihan Ramsey, Biliana Marcheva, Joseph Bass
    Pages 13-32
  4. Roda Rani Konadhode, Dheeraj Pelluru, Priyattam J. Shiromani
    Pages 33-45
  5. Ralph J. DiLeone, Nandakumar S. Narayanan, Douglas J. Guarnieri
    Pages 47-60
  6. Martin G. Myers Jr.
    Pages 75-87
  7. Chantelle N. Hart, Elizabeth S. Kuhl, Elissa Jelalian
    Pages 89-100
  8. Vidya Krishnan, Sanjay R. Patel
    Pages 119-131
  9. Silvana Pannain, Guglielmo Beccuti, Eve Van Cauter
    Pages 133-168
  10. Susan Redline
    Pages 179-189
  11. Dhiraj G. Kabra, Uma D. Kabra, Matthias H. Tschöp, Susanna Hofmann
    Pages 203-225
  12. Mark J. Perna, Thomas Karl Byrne, Chitharanja C. Pullattrana
    Pages 227-241
  13. Back Matter
    Pages 243-251

About this book


Sleep Loss and Obesity: Intersecting Epidemics  represents a major contribution to the field of sleep medicine.  It is a comprehensive review of the neurobiology of sleep, circadian timing and obesity, the deleterious effects of sleep loss and obesity on health.

The number of individuals who are obese has reached alarming levels.  As a result, the incidence of Type 2 diabetes, cardiovascular disorders, heart disease, and kidney failure have also increased.  The surgeon general estimates that the total annual cost of obesity in the US is about $117 billion.  This cost is expected to escalate significantly because the number of overweight and obese children is increasing rapidly.  Indeed, the new generation is expected to have a shorter life-span then their parents.  In addition, sleep loss is emerging as an important contributing factor to obesity.  People who sleep less or are sleep deprived tend to eat more, especially carbohydrates, and have a higher body mass index. Increased weight restricts the upper airway, causing obstructive sleep apnea and further sleep loss.  In the end there is a vicious cycle of weight gain and sleep loss.


In the past few years there has been a tremendous growth in our understanding of brain mechanisms controlling energy metabolism.  Interestingly the neurons regulating waking also regulate feeding.  There is also a mechanism that regulates the timing of feeding and sleep.  In shift-workers this system is likely to be disturbed, and this has an adverse impact on both feeding and sleep.


Sleep Loss and Obesity: Intersecting Epidemics is the first title to clearly examine how obesity and sleep loss are interacting epidemics. This fascinating title makes the link between energy metabolism, sleep and circadian timing; identifies poor sleep as a risk-factor for obesity in children and adults and offers treatment strategies for obstructive sleep apnea and obesity. This book will be a vital source of information for all physicians interested in sleep disorders and obesity. It will also be of value to neuroscientists, health system administrators, and policy makers.

Editors and affiliations

  • Priyattam Shiromani
    • 1
  • Tamas Horvath
    • 2
  • Susan Redline
    • 3
  • Eve Van Cauter
    • 4
  1. 1., Division of Sleep MedicineHarvard Medical SchoolWest RoxburyUSA
  2. 2., Section of Comparative MedicineYale University School of MedicineNew HavenUSA
  3. 3., Department of MedicineHarvard Medical School, Brigham and WomeBostonUSA
  4. 4., Department of MedicineThe University of ChicagoChicagoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine
  • Print ISBN 978-1-4614-3491-7
  • Online ISBN 978-1-4614-3492-4
  • Buy this book on publisher's site