Systems Biology of Parkinson's Disease

  • Peter Wellstead
  • Mathieu Cloutier

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Febe Francis, Míriam R. García, Richard H. Middleton
    Pages 81-109
  3. Fiachra B. Bolger, Niall J. Finnerty, John P. Lowry
    Pages 111-129
  4. Mathieu Cloutier, Peter Wellstead
    Pages 131-150
  5. Zhen Qi, Gary W. Miller, Eberhard O. Voit
    Pages 151-171
  6. Back Matter
    Pages 173-176

About this book


This text is the first to present a study of Parkinson’s disease from a Systems Biology perspective. By placing the condition at centre stage, the authors have been able to provide a wide ranging modelling and systems analysis that is focussed on a multi-facetted and highly complex condition. The book comprises a specially selected set of eight studies of important aspects of PD, covering all relevant scales of space and time. These are used to show how innovative sensing techniques, mathematical modelling, model analysis and computational simulation can throw new light on the dynamics of disease mechanisms that drive this important form of neurodegeneration.

Editors and affiliations

  • Peter Wellstead
    • 1
  • Mathieu Cloutier
    • 2
  1. 1., Hamilton InstituteNational University of Ireland, MaynoothMaynoothIreland
  2. 2.Ecole Polytechnique de MontrealMontrealCanada

Bibliographic information