Analysis of Genetic Association Studies

  • Gang Zheng
  • Yaning Yang
  • Xiaofeng Zhu
  • Robert C. Elston

Part of the Statistics for Biology and Health book series (SBH)

Table of contents

  1. Front Matter
    Pages I-XXII
  2. Background

    1. Front Matter
      Pages 1-1
    2. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 3-31
    3. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 33-58
  3. Single-Marker Analysis for Case-Control Data

    1. Front Matter
      Pages 59-59
    2. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 61-93
    3. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 95-120
    4. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 121-150
    5. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 151-206
  4. Multi-marker Analyses for Case-Control Data

    1. Front Matter
      Pages 207-207
    2. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 209-233
    3. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 235-256
  5. Topics Related to Analysis of Case-Control Association

    1. Front Matter
      Pages 257-257
    2. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 259-286
    3. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 287-308
    4. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 309-333
  6. Introduction to Genome-Wide Association Studies

    1. Front Matter
      Pages 335-335
    2. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 337-349
  7. Introduction to Family-Based Association Studies

    1. Front Matter
      Pages 351-351
    2. Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston
      Pages 353-387

About this book

Introduction

Analysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in Analysis of Genetic Association Studies particularly relevant.  The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology. 

 

In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications.  Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge.  The organization of this work allows for both casual reference and close study. 

Keywords

Association Studies Bayes Factors Case-control Data Genetic Epidemiology Robust Hypothesis Testing

Authors and affiliations

  • Gang Zheng
    • 1
  • Yaning Yang
    • 2
  • Xiaofeng Zhu
    • 3
  • Robert C. Elston
    • 4
  1. 1.National Heart, Lung, & Blood Institute, Office of Biostatistics ResearchNational Institutes of HealthBethesdaUSA
  2. 2.Technology of China, Dept. MathematicsUniversity of Science &HefeiChina, People's Republic
  3. 3.School of Medicine, Dept. Epidemiology & BiostatisticsCase Western Reserve UniversityClevelandUSA
  4. 4.School of Medicine, Dept. Epidemiology & BiostatisticsCase Western Reserve UniversityClevelandUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-2245-7
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, Boston, MA
  • eBook Packages Mathematics and Statistics
  • Print ISBN 978-1-4614-2244-0
  • Online ISBN 978-1-4614-2245-7
  • Series Print ISSN 1431-8776
  • About this book