Molecular Theory of the Living Cell

Concepts, Molecular Mechanisms, and Biomedical Applications

  • Sungchul Ji

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Introduction

    1. Sungchul Ji
      Pages 1-3
  3. Principles, Laws, and Concepts

    1. Front Matter
      Pages 5-5
    2. Sungchul Ji
      Pages 7-67
    3. Sungchul Ji
      Pages 69-84
    4. Sungchul Ji
      Pages 85-118
    5. Sungchul Ji
      Pages 119-157
    6. Sungchul Ji
      Pages 159-199
  4. Theories, Molecular Mechanisms, and Models

    1. Front Matter
      Pages 201-201
    2. Sungchul Ji
      Pages 231-253
    3. Sungchul Ji
      Pages 269-293
  5. Applications: From Molecules to Mind and Evolution

    1. Front Matter
      Pages 295-295
    2. Sungchul Ji
      Pages 297-390
    3. Sungchul Ji
      Pages 391-477
    4. Sungchul Ji
      Pages 479-485
    5. Sungchul Ji
      Pages 521-571
    6. Sungchul Ji
      Pages 573-583
    7. Sungchul Ji
      Pages 585-598
    8. Sungchul Ji
      Pages 599-606
    9. Sungchul Ji
      Pages 607-620
  6. Back Matter
    Pages 643-748

About this book


This book presents a comprehensive molecular theory of the living cell based on over thirty concepts, principles and laws imported from thermodynamics, statistical mechanics, quantum mechanics, chemical kinetics, informatics, computer science, linguistics, semiotics, and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for the basic living processes such as ligand-receptor interactions, protein folding, single-molecule enzymic catalysis, force-generating mechanisms in molecular motors, signal transduction, regulation of the genome-wide RNA metabolism, morphogenesis, the micro-macro coupling in coordination dynamics, the origin of life, and the mechanisms of biological evolution itself. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotheragnostics and personalized medicine.


Applications Cell biology Conceptual Foundations Molecular biology drug discovery pharmacotherapeutics theoretical biology

Authors and affiliations

  • Sungchul Ji
    • 1
  1. 1.Ernest Mario School of Pharmacy, Dept. of Pharmacology & ToxicologyRutgers UniversityPiscatawayUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-1-4614-2151-1
  • Online ISBN 978-1-4614-2152-8
  • Buy this book on publisher's site